Polysaccharids of kernel Avena sativa, Poaceae

Acute Toxicity: oral

Administrative data

Endpoint:

acute toxicity: oral

Type of information:

other: Weight of evidence approach

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Justification for type of information:

The weight of Evidence is justified in the attached Justification

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2008

Report date:

2008

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

other: OECD 432, OECD 129 and ECVAM 139

GLP compliance:

not specified

Test material

Test material information

1

Reference substance name:

Polysaccharids of kernel Avena sativa, Poaceae

EC Number:

944-507-3

IUPAC Name:

Polysaccharids of kernel Avena sativa, Poaceae

Results and discussion

Effect levels

Key result

Sex:

male/female

Dose descriptor:

LD50

Effect level:

> 2 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:

GHS criteria not met

Conclusions:

Based on these different information, the applicant concludes that the substance Polysaccharides of Avena Sativa kernel do not show acute oral systemic toxicity potentially up to 2000 mg/kg bw.Therefore, no classification for acute oral toxicity is needed.