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Physical & Chemical properties

pH

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Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard OECD test guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: OECD 122(pH measurement interface Microlab FS-524 and pH probe)
Principles of method if other than guideline:
The pH of an aqueous solution or dispersion in water is determined with a pH measurement interface equipped with an appropriate electrode system.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Tripiperazine dicitrate
EC Number:
205-622-8
EC Name:
Tripiperazine dicitrate
Cas Number:
144-29-6
Molecular formula:
C6H8O7.3/2C4H10N2
IUPAC Name:
piperazine 2-hydroxypropane-1,2,3-tricarboxylate (3:2) (salt)
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material (as cited in study report): Piperazine Citrate - Molecular formula: C12H30N6•Cl2H16O14 - Molecular weight: 642.76 g/mole - Smiles notation: C1CNCCN1.C1CNCCN1.C1CNCCN1.C(C(=O)O)C(CC(=O)O)(C(=O)O)O.C(C(=O)O)C(CC(=O)O)(C(=O)O)O - Substance type: Organic - Physical state: Solid-Purity:99.0% (BP)
Specific details on test material used for the study:
- Name of test material (as cited in study report): Piperazine citrate / tripiperazine dicitrate- Molecular formula: C12H30N6•Cl2H16O14 - Molecular weight: 642.76 g/mole - Substance type: Organic - Physical state: Solid

Results and discussion

pH value
Key result
pH value:
5.6
Temp.:
26.5 °C
Concentration:
1 other: % w/v
Remarks on result:
other: Acidic in nature

Any other information on results incl. tables

Temperature of 1% w/v test solution

-

26.5°C

pH (RESULT)

 

-

5.60

Inference

1.   Acidic

2.   Basic

3.   Neutral

 

Acidic

Applicant's summary and conclusion

Conclusions:
The pH determination of test item Tripiperazine dicitrate (CAS No. 144-29-6) was done following OECD guideline 122. pH of 1% w/v aqueous solution was measured with the help of pH meter/probe and it was observed to be 5.60 at 26.5 °C.
Executive summary:

The pH determination of test item Tripiperazine dicitrate(CAS No. 144-29-6) was done as per the test guideline OECD 122. The pH of the test solution was determined with the help of pH probe. The measurement interface was Micro Lab FS-524; software version 6.2 8b. The pH was found to be 5.60 at 26.5°C.