Tetraethylammonium chloride

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental result performed using standard methods of analysis.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Principles of method if other than guideline:

The Pour density and tapped density of powders” was determined by method as recommended in The International Pharmacopoeia, Fourth Edition, 2014

GLP compliance:

not specified

Type of method:

other: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014

Specific details on test material used for the study:

Name of the test chemical: Tetraethylammonium chloride
Molecular formula:C8H20ClN
Molecular weight: 165.706 g/mol
Smiles Notation: [N+](CC)(CC)(CC)CC.[ClH-]
InChI: 1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
Substance Type: Organic
Physical State: Hygroscopic white Powder

Key result

Type:

pour density

Density:

0.607 g/cm³

Temp.:

25.2 °C

Remarks on result:

other: at 965.2 hPa pressure

Key result

Type:

tap density

Density:

0.667 g/cm³

Temp.:

25.2 °C

Remarks on result:

other: at 965.2 hPa pressure

TEST ITEM DESCRIPTION AND RESULTS

FOR SOLIDS:

By Pour Density and Tapped Density Method:

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1st Reading	2nd Reading
Method	Test methods: Pour density and tapped density of powders”recommended in The International Pharmacopoeia, Fourth Edition, 2014
Principle of method	Pour Density:It is the ratio of known weight of test item and its volume in graduated glass cylinder. Tap Density:It is the difference between the volume of test item measured before & after tapping in the graduated glass cylinder.
Test temperature (°C)	-	25.0°C	25.5°C
Atmospheric pressure (in hPa)	-	963.8	966.7
Weight of test item(m)		20.020	20.020
Volume of measuring cylinder; readability in g		50ml; 1 ml	50 ml; 1 ml
Volume of test item without tapping (V)		32	34
Volume of test item after tapping ( V1)	After 10 tapping	31	33
	After 50 tapping	30	30
	After 100 tapping	30	30
	After 250 tapping	-	-
	After 500 tapping	-	-
	After 750 tapping	-	-

 

 

FOR SOLIDS:

By Pour Density and Tapped Density Method:

Parameters	Details	Calculated values		Average Density
		1st Calculation	2nd Calculation
Pour Density of test Item (g/cm³)	= m / V	0.6256	0.5888	0.6072
Tap density of test Item (g/cm³)	= m / V1	0.6673	0.6673	0.6673

 

Conclusions:

The mean pour density and tapped density of Tetraethylammonium chloride (CAS No. 56-34-8) was determined to be 0.6072 g/cm³ and 0.6673 g/cm³ at 25.2°C and 965.2 hPa.

Executive summary:

The density of test item Tetraethylammonium chloride (CAS No. 56-34-8) was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014

using bulk density apparatus. The mean pour density and tapped density of test item was determined to be 0.6072 g/cm³ and 0.6673 g/cm³ at 25.2°C and 965.2 hPa.

Description of key information

The mean pour density and tapped density of Tetraethylammonium chloride (CAS No. 56-34-8) was determined to be 0.6072 g/cm³ and 0.6673 g/cm³ at 25.2°C and 965.2 hPa.

Additional information

The density of test item Tetraethylammonium chloride (CAS No. 56-34-8) was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014

using bulk density apparatus. The mean pour density and tapped density of test item was determined to be 0.6072 g/cm³ and 0.6673 g/cm³ at 25.2°C and 965.2 hPa.