Registration Dossier
Registration Dossier
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EC number: 944-552-9 | CAS number: -
Endpoint summary
Administrative data
Description of key information
No data is available for Liraglutide precursor.
Data from OECD 404 guideline studies on MI3 (S3) and X14DesB30 (S4) indicate no potential for skin irritation. Due to very close structural similarity to Liraglutide precursor, a lack of skin irritation potential can be concluded for Liraglutide precursor as well.Data from OECD 405 guideline studies on MI3 (S3) and X14DesB30 (S4) indicate no potential for eye irritation. Due to very close structural similarity to Liraglutide precursor, a lack of eye irritation potential can be concluded for Liraglutide precursor as well.
For further read-across justification see docoment attached to section 13.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Based on read-across from in vivo data on MI3 (S3) and X13DesB30 (S4) Liraglutide precursor is not considered to be a skin or eye irritant. Thus, no CLP-classification should apply for skin and eye irritation of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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