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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Test start:16 January, 1990; Test end: 17 January, 1990; Study completion date: 31 January, 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: Sieving method
Version / remarks:
The test substance could not be analysed in accordance with the OECD Guideline for Testing of Chemicals No. 110 "Particle Size Distribution/Fibre Length and Diameter Distributions" because its particle size distribution is
too large to be analysed by any of the suggested methods.
Deviations:
no
Principles of method if other than guideline:
This test was performed by the sieving method. The measurements were performed on an "Alpine Luftstrahlsieb" using mesh sizes in accordance with DIN 4188. 0.5 to 20 g of the test substance are analysed with sieves of successively coarser mesh sizes. Sieving with each mesh size is repeated until less than 1 % change in weight of the residual substance is observed within 180 s sieving time.
GLP compliance:
no
Type of method:
sieving
Type of particle tested:
primary particle
Type of distribution:
mass based distribution
Specific details on test material used for the study:
SOURCE AND DETAILS OF TEST MATERIAL
- Identification: Methine Blue TRL; FAT no. 31'064/F
- Lot number of the test material: EN 158496.82/HEW 133/6
Storage: Room temperature, 20 - 24 °C
Mass median aerodynamic diameter:
ca. 98 µm
Percentile:
D50
Mean:
98 µm
Remarks on result:
other: Std deviation not reported
No.:
#1
Size:
1 000 µm
Distribution:
0.1 %
No.:
#2
Size:
400 µm
Distribution:
1 %
No.:
#3
Size:
200 µm
Distribution:
8 %
No.:
#4
Size:
100 µm
Distribution:
49 %
No.:
#5
Size:
40 µm
Distribution:
76 %
No.:
#6
Size:
20 µm
Distribution:
97 %

Particle shape (qualitatively): platelets

Mesh size (width)

Mass percent oversize

1000 µm

  0.1 %

400 µm

1%

200 µm

8%

100 µm

49%

40 µm

76%

20 µm

97%

The test substance contains a few large particles. Depending on whether some lumps come into the sieving sample or not, the results of subsequent siftings scatter considerably. For this reason, the average of all siftings is taken as the final result. Furthermore, since the large particles are very brittle and are therefore partially destroyed during long sieving operations, the sieving procedure was based on a constant sieving time of 8 minutes.

 

Largest particle size: 2x3x6 mm / 3x4x5 / 2x3x5 mm

Conclusions:
The median of mass distribution (width) for the test substance was determined to be 98 μm.
Executive summary:

A study was conducted wherein the particle size distribution of the test substance was evaluated using the seiving method. The test substance could not be analysed in accordance with the OECD Guideline for Testing of Chemicals No. 110 "Particle Size Distribution/Fibre Length and Diameter Distributions" because its particle size distribution is too large to be analysed by any of the suggested methods. The test substance contains a few large particles. Depending on whether some lumps come into the sieving sample or not, the results of subsequent sittings scatter considerably. For this reason, the average of all siftings is taken as the final result. Furthermore, since the large particles are very brittle and are therefore partially destroyed during long sieving operations, the sieving procedure was based on a constant sieving time of 8 minutes. Based on the findings of the study, the median of mass distribution (width) for the test substance was determined to be 98 μm.

Description of key information

A study was conducted wherein the particle size distribution of the test substance was evaluated using the seiving method. The test substance could not be analysed in accordance with the OECD Guideline for Testing of Chemicals No. 110 "Particle Size Distribution/Fibre Length and Diameter Distributions" because its particle size distribution is too large to be analysed by any of the suggested methods. The test substance contains a few large particles. Depending on whether some lumps come into the sieving sample or not, the results of subsequent sittings scatter considerably. For this reason, the average of all siftings is taken as the final result. Furthermore, since the large particles are very brittle and are therefore partially destroyed during long sieving operations, the sieving procedure was based on a constant sieving time of 8 minutes. Based on the findings of the study, the median of mass distribution (width) for the test substance was determined to be 98 μm.

Additional information