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EC number: 944-280-0
CAS number: -
No data is available on the substance
itself, thus the assessement of the biodegradation potential of the
target substance is done by using the Read Across approach. The
justification for Read Across is given in section 13 of IUCLID.
Two biodegradation tests (BOD5/COD)
perfomed under GLP conditions are available for Similar Substance 01.
The first study [Huntsman Textile
Effects (Germany) GmbH, 1992] was performed according to ISO 5815.
The test substance was incubated with seeding water of an urban waste
water at concetrations ranging between 806.9 and 6.3 mg/l for 5 days at
20 °C. The BOD5 of the test substance was determined to
be 4 mg O2/g.
The second study [Huntsman Textile
Effects (Germany) GmbH, 1991], was performed following the EU Method
C.6 ( EEC Directive 84/449). The test substance was chemically oxidised
with potassium dichromate at 148 °C for 2h. The amount of unreacted
potassium dichromate was determined by titration. The COD was calculated
as 1384 mg O2/g.
According to ECHA guidance r7b (version
4.0, June 2017), in addition to the OECD methods, there is a surrogate
procedure whereby if the BOD5:COD ratio is 0.5 or higher, the substance
is regarded as being readily biodegradable. In the case of the Similar
Substance 01, the same lot no was used in the two tests therefore the
BOD5:COD can be calculated for the substance. The BOD5:COD is equal to
0.003 suggesting that the substance is not expected to be readily
This expectation is confirmed by the data
set (attached) on other similar substances which have a different
salification from the Target Substance.
The studies selected as the most
representative and conservative were performed on Similar Substance 01.
The two tests were conducted under GLP conditions and according to
standard methods (ISO5815 and EU Method C.6). Other studies available on
the other similar substances were not described in detail and were not
used as the studies for the assessment of biodegradation potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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