Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 11, 2005 to July 01, 2005
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: OECD Guideline for Testing of Chemicals, No. 105, “Water solubility”; adopted July 27, 1995. EEC Directive 92/69, Part A, Methods for the determination of physico-chemical properties, A.6: “Water solubility”, EEC Publication No. L383, December 1992.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside
EC Number:
609-920-2
Cas Number:
4137-56-8
Molecular formula:
C16H22O7S
IUPAC Name:
Methyl 2,3-O-(1-methylethylidene)-5-O-[(4-methylphenyl)sulfonyl]-ß-D-ribofuranoside
Details on test material:
Identity: Tosylfuranosid
Appearance: Solid / white
Storage: At room temperature at about 20°C
Expiration date: July 31, 2005

Results and discussion

Water solubility
Water solubility:
25 mg/L
Temp.:
20 °C
pH:
>= 2.54 - <= 2.59

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of Tosylfuranosid at 20°C was determined to be 25 mg/l (standard deviation ± 1.15 mg/l).
Executive summary:

The purpose of the study was to evaluate the solubility of Tosylfuranosid in water, which is specified by the saturation mass concentration of the test item in water at a given temperature.

The water solubility of Tosylfuranosid at 20°C was determined to be 25 mg/l (standard deviation ± 1.15 mg/l).