Registration Dossier
Registration Dossier
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EC number: 908-998-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish
Four short-term toxicity to fish tests with three different species are available. The tests with salmo gairdneri shows a 96 h-LC50between 130 and 136 mg/L. The 96 h- LC50on Cyprinus carpio was found to be 142 mg/L. The 48 h LC0on Leuciscus idus was found to be between 218 and 282 mg/L.
All results are above 100 mg/L and therefore it can be concluded that the registered substance is not toxic to fish.
Short-term toxicity to Daphnia
No effects on Daphnia magna were observed at any of the tested pH-neutralised and un-neutralised concentration levels of 6.25 to 100 mg/L of the test item Hordaphos CC MIS and a pH-range of 5.18 to 7.77. Thus, the observed effects at the un-neutralised concentration level of 100 mg/L in the non GLP preliminary range finding test were induced by a pH-value of ≤ 4.63
Toxicity to algae
In this study, Hordaphos CC MIS was found not to inhibit the growth of the freshwater green alga Pseudokirchneriella subcapitata after 72 hours when tested with 100 mg/L and a pH adjusted to 8.1. The NOEC (0-72 h) for both inhibition of growth and inhibition of yield was 100 mg/L.
As the toxic effects are due to the pH value this was additionally investigated in a geometrical series of five test concentrations. Under these conditions, the following effect values were determined: The EC50-values with 95 % confidence intervals for inhibition of growth rate (ErC50) and yield (EyC50) after 72 hours were 35.3 (32.8 – 44.3) mg/L and 20.9 (19.3 – 22.6) mg/L, respectively. The NOEC-values for inhibition of both growth rate and yield after 72 hours were < 10.0 mg/L. All effect values are based on the nominal concentrations of Hordaphos CC MIS.
Toxicity to microorganisms
The NOEC of the Test item is 32 mg/L.The test item is not toxic up to the concentration of 32 mg/L to activated sludge of a municipal sewage treatment plant. The EC10 is 106 mg/L, the EC50 is 395 mg/L and EC80 is 708 mg/L of the test item.
Additional information
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