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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Appearance / physical state / colour:

The physical appearance of 4-methoxyphenylacetone is observed to be a colorless oily liquid organic compound with anise type odor and taste.

Melting point/ Freezing point:

The freezing point of 4-methoxyphenylacetone is determined to be less than -15°C.

Boiling point:

The boiling point of 4-methoxyphenylacetone is determined to be 268°C.

Density:

The density of 4-methoxyphenylacetone is determined to be 1.0694 g/cm3 at 17 °C.

Particle size distribution (Granulometry):

According to column 2 of AnnexVII of REAcH this end point was considered waiver since the 4-methoxyphenylacetone is a liquid substance and is expected to be marketed or used in a non solid or granular form.

Vapour pressure:

The estimated vapour pressure of the test substance 4-methoxyphenylacetone at 25 deg C was 1.37 Pa.

Partition coefficient:

Octanol water partition coefficient of the1-(4-methoxyphenyl)acetone(CAS no.122 -84 -9) was estimated. The estimated log POW of the1-(4-methoxyphenyl)acetonewas 1.55 dimesionless. On the basis of estimated value, the1-(4-methoxyphenyl)acetonecan be considered as hydrophilic in nature.

Water solubility:

The estimated water solubility of test substance 4-methoxyphenylacetone at 25 deg C was 3084 mg/l.

Surface tension:

Based on the prediction done by ACD labs, the surface tension for chemical 4-methoxyphenylacetone was predicted to be 33.7 ± 3.0 dyne/cm.

Flash point:

The flash point of 4-methoxyphenylacetone was estimated as 101.7 ± 0.0 °C.

Autoflammability:

4-methoxyphenylacetone did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 4-methoxyphenylacetone is not auto-flammable.

Flammability:

4-methoxyphenylacetone does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-methoxyphenylacetone is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-methoxyphenylacetone was considered non-flammable for chemical safety assessment.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidising properties:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidizing properties and hence the classification procedure does not need to be applied.

Additional information

Appearance / physical state / colour:

Based on available data from handbooks and secondary source, the physical appearance of 4-methoxyphenylacetone is observed to be a colorless oily liquid organic compound with anise type odor and taste.

Melting point/ Freezing point:

Based on available data from handbook and authoritative databases, the freezing point of 4-methoxyphenylacetone is determined to be less than -15°C.

Boiling point:

Based on available data from handbooks and authoritative databases, the boiling point of 4-methoxyphenylacetone is determined to be 268°C.

Other supporting data from handbooks and secondary source, also supported the selected key study and exhibited the boiling point of 4-methoxyphenylacetone in the range of 264 - 265 °C and 260 °C respectively, closer to the selected key value.

Density:

Based on available data from handbook, the density of 4-methoxyphenylacetone is determined to be 1.0694 g/cm3 at 17 °C.

Other supporting data from handbook, exhibited the density of 4-methoxyphenylacetone as 1.081 g/cm3 at 0 °C and 1.067 g/cm3 at 18 °C.

One more supporting data from authoritative database Scifinder, also determined the density of 4-methoxyphenylacetone as 1.095 g/cm3 at 0 °C.

Particle size distribution (Granulometry):

According to column 2 of AnnexVII of REAcH this end point was considered waiver since the 4-methoxyphenylacetone is a liquid substance and is expected to be marketed or used in a non solid or granular form.

Vapour pressure:

Modified Grain method (Mean of Antoine and Modified Grain methods) was used to estimate the vapour pressure of the test substance 4-methoxyphenylacetone using MPBPVP v1.43 of EPI SUITE.

The estimated vapour pressure of the test substance 4-methoxyphenylacetone at 25 deg C was 1.37 Pa.

Partition coefficient:

Octanol water partition coefficient of the1-(4-methoxyphenyl)acetone(CAS no.122 -84 -9) was estimated. The estimated log POW of the1-(4-methoxyphenyl)acetonewas 1.55 dimesionless. On the basis of estimated value, the1-(4-methoxyphenyl)acetonecan be considered as hydrophilic in nature.

Water solubility:

WSKOW v1.42 was used to estimate the water solubility of the test substance 4-methoxyphenylacetone.

The estimated water solubility of the test substance 4-methoxyphenylacetone at 25 deg C was 3084 mg/l.

Other supporting data from authoritative database, also estimated the water solubility of 4-methoxyphenylacetone as 7966 mg/L at 25 °C.

Based on the estimated values, the test substance 4-methoxyphenylacetone was considered to be soluble in water.

Surface tension:

Based on the prediction done by ACD labs Software (v12.1.0.50375), the surface tension for chemical 4-methoxyphenylacetone was predicted to be 33.7 ± 3.0 dyne/cm.

Flash point:

Based on available data from authoritative database Scifinder, the flash point of 4-methoxyphenylacetone was estimated as 101.7 ± 0.0 °C.

Thus accroding to estimated value the given chemical was not classified as flammable.

Autoflammability:

4-methoxyphenylacetone did not catch fire on being exposed to air at room temperature of 27°C pressure of 966 hPa. This indicates that 4-methoxyphenylacetone is not auto-flammable.

Flammability:

4-methoxyphenylacetone does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 4-methoxyphenylacetone is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 4-methoxyphenylacetone was considered non-flammable for chemical safety assessment.

Explosiveness:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidising properties:

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidizing properties and hence the classification procedure does not need to be applied.