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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data isfrom modelling databases.
Qualifier:
according to guideline
Guideline:
other: refer principle below
Principles of method if other than guideline:
To estimate Octanol water partition coefficent of test chemical 1-(4-methoxyphenyl)acetone.
GLP compliance:
not specified
Type of method:
other: estimation
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
- Name of test material: 4-methoxyphenylacetone
- IUPAC name: 1-(4-methoxyphenyl)acetone
- Molecular formula: C10H12O2
- Molecular weight: 164.203 g/mole
- Smiles : c1(ccc(OC)cc1)CC(C)=O
- Inchl: 1S/C10H12O2/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6H,7H2,1-2H3
- Substance type: Organic
- Physical state: Colorless, oily liquid
Key result
Type:
log Pow
Partition coefficient:
1.55
Temp.:
25 °C
Remarks on result:
other: other details not available
Conclusions:
The estimated log Pow of target chemical 1-(4-methoxyphenyl)acetoneis 1.55 dimensionless by this value this chemical is considered as hydrophilic in nature.
Executive summary:

Octanol water partition coefficient of the 1-(4-methoxyphenyl)acetone (CAS no.122 -84 -9) was estimated. The estimated log POW of the 1-(4-methoxyphenyl)acetone was 1.55 dimesionless. On the basis of estimated value, the 1-(4-methoxyphenyl)acetone can be considered as hydrophilic in nature.

Description of key information

Octanol water partition coefficient of the1-(4-methoxyphenyl)acetone (CAS no.122 -84 -9) was estimated. The estimated log POW of the1-(4-methoxyphenyl)acetonewas 1.55 dimesionless. On the basis of estimated value, the1-(4-methoxyphenyl)acetone can be considered as hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.55
at the temperature of:
25 °C

Additional information

Octanol water partition coefficient of the1-(4-methoxyphenyl)acetone (CAS no.122 -84 -9) was estimated. The estimated log POW of the1-(4-methoxyphenyl)acetonewas 1.55 dimesionless. On the basis of estimated value, the1-(4-methoxyphenyl)acetone can be considered as hydrophilic in nature.