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EC number: 245-612-0 | CAS number: 23363-14-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 December 2012 to 07 February 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Read-across performed with structurally similar substance.
- Reason / purpose for cross-reference:
- other: read-across target
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): local wastewater treatment plant (ARA Ergolz II, Füllinsdorf / Switzerland) treating predominantly domestic sewage.
- Preparation of inoculum for exposure:
* sludge was washed twice with tap water by centrifugation and the supernatant liquid phase was decanted.
* a homogenised aliquot of the final sludge suspension was weighed, thereafter dried and the ratio of wet to dry weight was calculated.
* during the holding period of one day prior to use, the sludge was aerated at room temperature.
* prior to use, the sludge was diluted with test water to a concentration of about 1 g dw/L.
* defined volumes of this diluted activated sludge were added to test water to obtain a final concentration of 30 mg dw/L. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 30 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of the medium: according to the OECD guideline
- Test temperature: 21 to 24°C.
- pH: Prior to test start (Day 0), the pH was measured in each test flask after the addition of test and/or reference item and adjusted to 7.3 with a 1M sodium hydroxide solution.
- pH adjusted: yes
- Suspended solids concentration: not reported
- Continuous darkness: yes. The test vessels were incubated in a dark room
TEST SYSTEM
- Culturing apparatus: 5-litre all-glass amber bottles
- Number of culture flasks/concentration: Two absorber flasks, the first one containing 300 mL 0.05 M NaOH and the second one containing 200 mL 0.05 M NaOH.
- Measuring equipment: TOC analyser
- Test performed in closed vessels due to significant volatility of test substance: No
- Test performed in open system: yes
SAMPLING
- Sampling frequency: samples were taken on Exposure Day 2, 5, 7, 9, 12, 14, 19, 21, 28, and 29.
- Sampling method: an aliquot of 5.0 mL was withdrawn from the absorber flask nearest to the test flask for analysis of inorganic carbon. Additional samples for analysis of IC were withdrawn from the second absorber flask of all test vessels on Exposure Day 14 and at the end of the exposure period on Exposure Day 28 in order to correct for any carry over of CO2.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Toxicity control: yes - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 77
- Sampling time:
- 28 d
- Details on results:
- The CO2 formation of the test material, Lanthanum Acetate, in the test media significantly increased from the start of the test until Exposure Day 19, when the mean biodegradation reached 75%. At the end of the 28 day exposure period, average biodegradation was 77%.
Toxicity control: > 25% degradation after 28 days, confirming that test material was not toxic to the microorganisms in the test. - Results with reference substance:
- By the end of the test (Exposure Day 28), average biodegradation was 90 %.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- A CO2 evolution test (OECD 301B) demonstrated that the test material, lanthanum acetate, is readily biodegradable, passing the 10-d time window criterium (pass level = 60%). It must be kept in mind that this refers to the organic part of the molecule (acetate), since La itself is not biodegradable (endpoint not relevant for inorganic part of substance). The results of the test can be considered reliable without restrictions.
- Executive summary:
The ready biodegradability of the test material was determined in accordance with the standardised guideline OECD 301B, under GLP conditions.
A CO2 evolution test (OECD 301B) demonstrated that the test material, lanthanum acetate, is readily biodegradable (77%), passing the 10-d time window criterium (pass level = 60%). It must be kept in mind that this refers to the organic part of the molecule (acetate), since La itself is not biodegradable (endpoint not relevant for inorganic part of substance).
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted on read-across material
- Justification for type of information:
- Read-across performed with structurally similar substance.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 77
- Sampling time:
- 28 d
Referenceopen allclose all
Description of key information
Read-across performed with structurally similar substance.
A CO2 evolution test (OECD 301B) demonstrated that the test material, lanthanum acetate, is readily biodegradable (77%), passing the 10-d time window criterium (pass level = 60%). It must be kept in mind that this refers to the organic part of the molecule (acetate), since La itself is not biodegradable (endpoint not relevant for inorganic part of substance).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Read-across performed with structurally similar substance.
The ready biodegradability of the test material was determined in accordance with the standardised guideline OECD 301B, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
A CO2 evolution test (OECD 301B) demonstrated that the test material, lanthanum acetate, is readily biodegradable (77%), passing the 10-d time window criterium (pass level = 60%). It must be kept in mind that this refers to the organic part of the molecule (acetate), since La itself is not biodegradable (endpoint not relevant for inorganic part of substance).
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