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EC number: 296-719-4 | CAS number: 93028-28-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Between 09 February 1981 and 16 February 1981
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 981
- Report date:
- 1981
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: Section 1500.42 Federal Hazardous Substances Act Regulations - CFR 16 P. 125.
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 61789-86-4
- IUPAC Name:
- 61789-86-4
- Reference substance name:
- Sulfonic acids, petroleum, calcium salts
- EC Number:
- 263-093-9
- EC Name:
- Sulfonic acids, petroleum, calcium salts
- IUPAC Name:
- 263-093-9
- Details on test material:
- Identification: OS#47860
Date received: 28 January 1981
Constituent 1
Constituent 2
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
- Details on test animals or tissues and environmental conditions:
- Six healthy young adult albino rabbits were used in this study.
The animals were housed and maintained in compliance with the Animal Welfare Act (Pub. L-94-279) 9 CFR Part 3.
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- other: The left eye remained untreated and was used for control purposes.
- Amount / concentration applied:
- 0.1 gm of the experimental material was instilled into the right eye.
- Duration of treatment / exposure:
- The test material was not washed from the eyes.
- Observation period (in vivo):
- The treated eyes were examined at one, two, three, five and seven days following instillation of the test material into the eyes.
- Number of animals or in vitro replicates:
- 6
- Details on study design:
- Six healthy young adult albino rabbits were used in this study.
0.1 gm of the experimental material was instilled into the right eyes of the test animals while the other eyes remained untreated to serve as controls. The test material was not washed from the eyes.
The treated eyes were examined at one, two, three, five and seven days following instillation of the test material into the eyes. Interpretation of the results was made in accordance with the Draize Scale of Scoring Ocular Lesions - see attachment 1.
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: Day 1
- Score:
- 0
- Max. score:
- 110
- Reversibility:
- other: No effects observed
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: Day 2
- Score:
- 0
- Max. score:
- 110
- Reversibility:
- not specified
- Remarks:
- No effects observed
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: Day 3
- Score:
- 0
- Max. score:
- 110
- Reversibility:
- other: No effects observed
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: Day 5
- Score:
- 0
- Max. score:
- 110
- Reversibility:
- other: No effects observed
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: Day 7
- Score:
- 0
- Max. score:
- 110
- Reversibility:
- other: No effects observed
- Irritant / corrosive response data:
- Based on the accompanying table, the subject material is not a primary irritant within the definition of the Act Reference Section 1500.42 (b) (1) (2), and requires no cautionary labeling with respect to that section.
See Table 1 - attachment 2
Any other information on results incl. tables
See Table 1 - attachment 2
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: other: Based on the accompanying table, the subject material is not a primary irritant within the definition of the Act Reference Section 1500.42 (b) (1) (2), and requires no cautionary labeling with respect to that section.
- Conclusions:
- Based on the accompanying table, the subject material is not a primary irritant within the definition of the Act Reference Section 1500.42 (b) (1) (2), and requires no cautionary labeling with respect to that section.
- Executive summary:
To determine the degree of irritation,if any, which the subject material may produce when instilled into the eyes of albino rabbits.
Six healthy young adult albino rabbits were used in this study. 0.1 gm of the experimental material was instilled into the right eyes of the test animals while the other eyes remained untreated to serve as controls. The test material was not washed from the eyes. The treated eyes were examined at one, two, three, five and seven days following instillation of the test material into the eyes. Interpretation of the results was made in accordance with the Draize Scale of Scoring Ocular Lesions.
Based on the accompanying table, the subject material is not a primary irritant within the definition of the Act Reference Section 1500.42 (b) (1) (2), and requires no cautionary labeling with respect to that section.
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