Registration Dossier
Registration Dossier
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EC number: 202-711-3 | CAS number: 98-89-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 1986
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The data obtained from a source of secondary literature are related to a substance which shows the same functional groups . The data derived from read-across is considered reliable because the molecules have the same functional groups due to the action irritating.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- 3-Cyclohexene-1-carboxylic acid
- Year:
- 2 013
- Bibliographic source:
- CHEMIDplus
- Reference Type:
- secondary source
- Title:
- 3-Cyclohexene-1-carboxylic acid
- Year:
- 2 013
- Bibliographic source:
- RTECS
- Reference Type:
- publication
- Title:
- No information
- Year:
- 1 986
- Bibliographic source:
- Prehled Prumyslove Toxikologie; Organicke Latky,' Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 (-,315,1986)
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-Cyclohexene-1-carboxylic acid
- IUPAC Name:
- 3-Cyclohexene-1-carboxylic acid
- Reference substance name:
- Cyclohex-3-ene-1-carboxylic acid
- EC Number:
- 225-314-7
- EC Name:
- Cyclohex-3-ene-1-carboxylic acid
- Cas Number:
- 4771-80-6
- Molecular formula:
- C7H10O2
- IUPAC Name:
- cyclohex-3-ene-1-carboxylic acid
- Test material form:
- not specified
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- other: REACTION: Severe
- Irritant / corrosive response data:
- REACTION: Severe
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance is classified for this property.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
