Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 December 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
Regulation EC No. 440/2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Version / remarks:
2002
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
air comparison pycnometer (for solids)

Test material

Constituent 1
Chemical structure
Reference substance name:
Adenosine 5'-(tetrahydrogen triphosphate), disodium salt
EC Number:
213-579-1
EC Name:
Adenosine 5'-(tetrahydrogen triphosphate), disodium salt
Cas Number:
987-65-5
Molecular formula:
C10H14N5O13P3.2Na
IUPAC Name:
disodium 9-{5-O-[hydroxy({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphoryl]pentofuranosyl}-9H-purin-6-amine
impurity 1
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
Oxidane
impurity 2
Reference substance name:
Unknown impurities.
Molecular formula:
Not available as unknown impurities.
IUPAC Name:
Unknown impurities.
Test material form:
solid: crystalline
Details on test material:
Storage conditions: 2-8°C
Batch No: 11678500

Results and discussion

Density
Key result
Type:
relative density
Density:
1.85 other: dimensionless
Temp.:
20 °C
Remarks on result:
other: the density of the test item is given as the mean value of two measurements normalized to the density of water

Any other information on results incl. tables

The individual relative density measurements were 1.84849 g/cm³ (test 1) and 1.85073 g/cm³ (test 2)

Applicant's summary and conclusion

Conclusions:
According to OECD Test Guidelines 109 (2012) and EC No. 440/2008 Part A. Method A.3., and OCSPP Test Guideline 830.7300 (2002), the relative density of the test item ATP, Di-Na (CAS no. 987-65-5) at 20 °C ±0.01 °C (compared to water at 4 °C) was determined to be 1.850.
Executive summary:

According to OECD Test Guideline 109 (2012), Regulation EC No. 440/2008 Method A.3. and OCSPP Test Guideline 830.7300 (2002), the relative density D420 of the test item ATP, Di-Na (CAS no. 987-65-5) at 20 °C ±0.01 °C (compared to water at 4 °C) is D420 = 1.850.