Phenol, mono-C24-28 (even)-sec-alkyl derivs, ortho- and para-

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

18 January 2017 to 10 February 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

< 0.001 other: gTOC/L

Conc. based on:

test mat.

Loading of aqueous phase:

0.1 g/L

Incubation duration:

>= 24 - <= 72 h

Temp.:

20 °C

pH:

5.8

Details on results:

PRELIMINARY TEST
- The preliminary estimate of water solubility using a loading rate of 0.1 g/L was < 1.0 x 10E-03 gTOC/L at 20.0 ± 0.5 °C and pH 5.8.
- The preliminary estimate of water solubility using a loading rate of 1 g/L was < 2.03 x 10E-02 gTOC/L at 20.0 ± 0.5 °C and pH 5.8.

DEFINITIVE TEST
- The analysed concentrations of total organic carbon (TOC) obtained from the sample solutions and blanks are shown in Table 14 (below).
- Concentration (g/L) of TOC in the sample solutions at 20.0 ± 0.5 °C are shown in Table 15 (below).

TABLE 14 – ANALYSED TOC CONCENTRATIONS IN THE MAIN TEST

Sample	Concentration (mgTOC/L)
Matrix blank A	0.2519
Matrix blank B	0.3279
Sample 1A	0.5135
Sample 1B	0.4652
Sample 2A	0.4446
Sample 2B	0.4241
Sample 3A	0.5554
Sample 3B	0.5455

 

TABLE 15– CONCENTRATION OF TOC IN SAMPLE SOLUTIONS

Sample number	Concentration (gTOC/L)	Solution pH
1	< 1.0 x 10^-3	5.2
2	< 1.0 x 10^-3	5.2
3	< 1.0 x 10^-3	5.2

Overall result: < 1.0 x 10E-03 gTOC/L at 20.0 ± 0.5 °C

Conclusions:

Water solubility of the test item was determinedby total organic carbonto be < 1.0 x 10E-03 g/L of solution at 20.0 ± 0.5 °C. The result was based on a nominal loading rate of 0.1 g/L.

Executive summary:

GUIDELINE

The determination was carried out using the flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

 

RESULTS

Water solubility of the test item was determinedby total organic carbon to be < 1.0 x 10E-03 g/L of solution at 20.0 ± 0.5 °C. The result was based on a nominal loading rate of 0.1 g/L.

Description of key information

Water solubility of the test item was determined by total organic carbon to be < 1.0 x 10E-03 g/L of solution at 20.0 ± 0.5 °C. The result was based on a nominal loading rate of 0.1 g/L (OECD 105 and EU Method A.6).

Additional information

GUIDELINE

The determination was carried out using the flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

 

RESULTS

Water solubility of the test item was determinedby total organic carbon to be < 1.0 x 10E-03 g/L of solution at 20.0 ± 0.5 °C. The result was based on a nominal loading rate of 0.1 g/L.