Registration Dossier
Registration Dossier
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EC number: 205-450-3 | CAS number: 141-04-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1969
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 969
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- no
Test material
- Reference substance name:
- Diisobutyl adipate
- EC Number:
- 205-450-3
- EC Name:
- Diisobutyl adipate
- Cas Number:
- 141-04-8
- Molecular formula:
- C14H26O4
- IUPAC Name:
- diisobutyl adipate
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
Test system
- Vehicle:
- unchanged (no vehicle)
- Amount / concentration applied:
- 100 %
- Duration of treatment / exposure:
- Twice a day for 14 days
- Observation period:
- 14 days
Results and discussion
In vivo
Results
- Irritation parameter:
- other: histopatological observation
- Basis:
- mean
- Time point:
- 14 d
- Reversibility:
- fully reversible
- Remarks on result:
- no indication of irritation
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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