Disodium β-glycerophosphate

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

27 July 2017 - 13 November 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

Disodium β-glycerophosphate

EC Number:

212-464-3

EC Name:

Disodium β-glycerophosphate

Cas Number:

819-83-0

Molecular formula:

C3H7O6P.2Na

IUPAC Name:

disodium β-glycerophosphate

impurity 1

Reference substance name:

Disodium α-glycerophosphate

EC Number:

216-304-3

EC Name:

Disodium α-glycerophosphate

Cas Number:

1555-56-2

Molecular formula:

C3H9O6P.2Na

IUPAC Name:

disodium 2,3-dihydroxypropyl phosphate

impurity 2

Reference substance name:

Water

EC Number:

231-791-2

EC Name:

Water

Cas Number:

7732-18-5

Molecular formula:

H2O

IUPAC Name:

Oxidane

Test material form:

solid: particulate/powder

Details on test material:

Batch No.: 11769400
Storage: 15-25°C

Results and discussion

Boiling point

Key result

Atm. press.:

1 009 hPa

Decomposition:

yes

Decomp. temp.:

ca. 50 °C

Remarks on result:

other: Boiling of the test item was not observed below the temperature of decomposition, therefore the test item has no boiling point.

Any other information on results incl. tables

Starting at a temperature of 50 °C a first exothermic effect with an energy release of -30 J/g can be observed. This effect is directly followed by an endothermic effect, starting at 70 °C. A second endothermic effect is detected starting at a temperature of 250 °C. Subsequently a second exothermic effect starting at 340 °C with an energy release of -50 J/g is observed.

During the heating phase two endothermic effects were observed in the temperature range of 70 – 130 °C and 250 – 330 °C, which cannot be assigned to the melting of the test item, because an exothermic effect is observed previously at 50 °C. In correlation to the determination of the thermal stability (see 4.19), the test item showed a decomposition starting at approx. 50 °C. Thus, no boiling of the test item could be detected up to its decomposition starting at 50 °C under atmospheric pressure. The detailed results of the DSC-measurements are given in the table in the field 'Overall remarks'.

Applicant's summary and conclusion

Conclusions:

The test item Disodium beta-glycerophosphat (CAS no. 819-83-0) has no boiling point up to the decomposition of temperature of approx. 50°C at atmospheric pressure (1009 hPa) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).

Executive summary:

The test item Disodium beta-glycerophosphat (CAS no. 819-83-0) has no boiling point up to the decomposition temperature of approx. 50°C at atmospheric pressure (1009 hPa) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).