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Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
27 July 2017 - 13 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
Disodium β-glycerophosphate
EC Number:
212-464-3
EC Name:
Disodium β-glycerophosphate
Cas Number:
819-83-0
Molecular formula:
C3H7O6P.2Na
IUPAC Name:
disodium 2,3-dihydroxypropyl phosphate
impurity 1
Chemical structure
Reference substance name:
Disodium α-glycerophosphate
EC Number:
216-304-3
EC Name:
Disodium α-glycerophosphate
Cas Number:
1555-56-2
Molecular formula:
C3H9O6P.2Na
IUPAC Name:
disodium 2,3-dihydroxypropyl phosphate
impurity 2
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
Oxidane
Test material form:
solid: particulate/powder
Details on test material:
Batch No.: 11769400
Storage: 15-25°C

Results and discussion

Boiling point
Key result
Atm. press.:
1 009 hPa
Decomposition:
yes
Decomp. temp.:
ca. 50 °C
Remarks on result:
other: Boiling of the test item was not observed below the temperature of decomposition, therefore the test item has no boiling point.

Any other information on results incl. tables

Starting at a temperature of 50 °C a first exothermic effect with an energy release of -30 J/g can be observed. This effect is directly followed by an endothermic effect, starting at 70 °C. A second endothermic effect is detected starting at a temperature of 250 °C. Subsequently a second exothermic effect starting at 340 °C with an energy release of -50 J/g is observed.

During the heating phase two endothermic effects were observed in the temperature range of 70 – 130 °C and 250 – 330 °C, which cannot be assigned to the melting of the test item, because an exothermic effect is observed previously at 50 °C. In correlation to the determination of the thermal stability (see 4.19), the test item showed a decomposition starting at approx. 50 °C. Thus, no boiling of the test item could be detected up to its decomposition starting at 50 °C under atmospheric pressure. The detailed results of the DSC-measurements are given in the table in the field 'Overall remarks'.

Applicant's summary and conclusion

Conclusions:
The test item Disodium beta-glycerophosphat (CAS no. 819-83-0) has no boiling point up to the decomposition of temperature of approx. 50°C at atmospheric pressure (1009 hPa) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).
Executive summary:

The test item Disodium beta-glycerophosphat (CAS no. 819-83-0) has no boiling point up to the decomposition temperature of approx. 50°C at atmospheric pressure (1009 hPa) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).

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