Registration Dossier
Registration Dossier
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EC number: 240-040-8 | CAS number: 15901-40-3
Endpoint summary
Administrative data
Description of key information
Additional information
Measured short term toxicity data with the registration substance are available for fish, invertebrates and algae.
The key values are:
Fish: A 96-hour EC50 value of >100 mg/l and a NOEC value of ≥100 mg/l (>LoS) (nominal) (only concentration tested) have been determined for the effects of N,N’,N’’-tricyclohexyl-1-methylsilanetriamine on mortality of Danio rerio, in compliance with OECD Test Guideline 203, Fish, acute toxicity test. Due to the rapid hydrolysis of the test substance it is expected that the organisms were exposed to the hydrolysis products.
Invertebrates:
A 48-hour EC50 value of >2.5 mg/l (>LoS) (nominal) (maximum concentration tested based on maximum solubility) has been determined for the effects of N,N’,N’’-tricyclohexyl-1-methylsilanetriamine on mobility of Daphnia magna, in compliance with OECD Test Guideline 202, Daphnia sp. acute immobilisation test. Due to the rapid hydrolysis of the test substance it is expected that the organisms were exposed to the hydrolysis products.
Algae: A 72-hour EC50 value of >2.5 mg/l, an EC10 of >2.5 mg/l and a NOEC of 2.5 mg/l (>LoS) (nominal) (maximum concentration tested based on maximum solubility) have been determined for the effects of N,N’,N’’-tricyclohexyl-1-methylsilanetriamine on growth rate of Pseudokirchneriella subcapitata, in compliance with OECD Test Guideline 201, Freshwater Alga and Cyanobacteria, Growth Inhibition Test. Due to the rapid hydrolysis of the test substance it is expected that the organisms were exposed to the hydrolysis products.
Due to the rapid hydrolysis rate of the parent substance, and the higher water solubility of the hydrolysis products, it is not appropriate to re-interpret these studies to derive conclusions about the toxicity of the hydrolysis products. Data in the form of studies conducted with other substances have therefore been read across for the hydrolysis products methylsilanetriol (CAS 2445-53-6) and cyclohexylamine (CAS 108-91-8) for the purpose of chemical safety assessment for the environment.
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