Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 601-779-5 | CAS number: 121451-02-3
Endpoint summary
Administrative data
Description of key information
Abiotic Degradation by Hydrolysis
The hydrolysis of the test material was investigated in a study conducted in accordance with the standardised guidelines OECD 111, EU Method C.7 and US EPA 161-1 under GLP conditions. The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as defined in Klimisch et al. (1997).
The rate and route of hydrolysis was studied at pH 5, 7, and 9 using [14C]radiolabelled material. The pseudo first-order rate constant was determined and used to calculate the half-life and DT90 of hydrolysis at pH 9. The second-order rate constant at pH 9 was calculated and used to predict degradation rates at various pH values, and degradates approaching or exceeding 10 % of applied radiocarbon were identified.
The test material was degraded via base-catalysed hydrolysis. Following 7 days of incubation at 50 °C, it was stable to hydrolysis at pH 5 (93.7 % remaining), slightly hydrolysed at pH 7 (78.6 % remaining) and mostly hydrolysed at pH 9 (8.5 % remaining). At 25°C the test material was stable to hydrolysis at pH 5 and 7. At pH 9, the pseudo-first order rate constant of the test material hydrolysis was 0.036 days-1giving half-life and DT90 values of 19 days and 64 days, respectively. The second-order rate constant of hydrolysis was 3600 days-1M-1, giving predicted half-life values of 0.19 days at pH 11 to 1930 days at pH 7. At pH 9, the test material was hydrolysed to form urea, amine, amide, and difluorobenzoic acid forms of the parent material.
Phototransformation in Water
The potential of the test material to undergo photolysis was investigated in a study conducted in accordance with the standardised guidelines with the US EPS 161-2, SETAC-Europe Procedures for Assessing the Environmental Fate and Ecotoxicity of Pesticides, Part 1, Section 10.0 and OPPTS 835.2210 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Under the conditions of this study, the test material photodegraded in buffered water and natural water with a theoretical half-life of 153 and 41 days, respectively, under summer sunlight at 40° N latitude.
Additional information
Abiotic Degradation by Hydrolysis
The hydrolysis of the test material was investigated in a study conducted in accordance with the standardised guidelines OECD 111, EU Method C.7 and US EPA 161-1 under GLP conditions. The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as defined in Klimisch et al. (1997).
The rate and route of hydrolysis was studied at pH 5, 7, and 9 using [14C]radiolabelled material. The pseudo first-order rate constant was determined and used to calculate the half-life and DT90 of hydrolysis at pH 9. The second-order rate constant at pH 9 was calculated and used to predict degradation rates at various pH values, and degradates approaching or exceeding 10 % of applied radiocarbon were identified.
The test material was degraded via base-catalysed hydrolysis. Following 7 days of incubation at 50 °C, it was stable to hydrolysis at pH 5 (93.7 % remaining), slightly hydrolysed at pH 7 (78.6 % remaining) and mostly hydrolysed at pH 9 (8.5 % remaining). At 25°C the test material was stable to hydrolysis at pH 5 and 7. At pH 9, the pseudo-first order rate constant of the test material hydrolysis was 0.036 days-1giving half-life and DT90 values of 19 days and 64 days, respectively. The second-order rate constant of hydrolysis was 3600 days-1M-1, giving predicted half-life values of 0.19 days at pH 11 to 1930 days at pH 7. At pH 9, the test material was hydrolysed to form urea, amine, amide, and difluorobenzoic acid forms of the parent material.
Phototransformation in Water
The potential of the test material to undergo photolysis was investigated in a study conducted in accordance with the standardised guidelines with the US EPS 161-2, SETAC-Europe Procedures for Assessing the Environmental Fate and Ecotoxicity of Pesticides, Part 1, Section 10.0 and OPPTS 835.2210 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Under the conditions of this study, the test material photodegraded in buffered water and natural water with a theoretical half-life of 153 and 41 days, respectively, under summer sunlight at 40° N latitude.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
