Registration Dossier
Registration Dossier
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EC number: 947-659-9 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
According to Annex XI section 1 of Regulation (EC) No 1907/2006 (REACH) testing of biodegradability is scientifically not justified because there is reliable data substantiating the conclusion that the substance is readily biodegradabiliy.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
No data is available on the biodegradability of the reaction mass of N-glycyl-L-tyrosine hydrochloride and potassium chloride. However, information on all relevant individual components indicate that the substance is readily biodegradable.
N-glycyl-L-tyrosine is utilized by microorgansisms as carbon source for energy production and thus, it is first enzymatically hydrolysed and subsequently its constituents are metabolised. Short peptides were taken up by microorganisms and were subsequently hydrolyzed or as an alternative peptidases were secreted and free amino acids were taken up. The hydrolyzed monomers are both natural occurring free amino acids. Glycine is readily biodegradable (see glycine registration dossier) and several aqueous aerobic biological screening studies have demonstrated that tyrosine is also readily biodegradable. Therefore, it can be judged with high confidence that also the dipeptide glycyl-L-tyrosine is readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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