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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

At pH 7 at 50.8°C: 6.5% loss in 5 days, Rate constant: 0.0156 d-1, Half life: 44.4 days (Greenwood 2003; EU method Annex V, C7 (92/69/EEC)).

At pH 9 at 50.8°C: 2.1% loss in 5 days, Rate constant: 0.0186 d-1, Half life: 37.4 days (Greenwood 2003; EU method Annex V, C7 (92/69/EEC)).

Key value for chemical safety assessment

Additional information

One study was performed according to EU method Annex V, C7 (92/69/EEC) regarding the hydrolysis of test item Chlorophene (CAS 120-32-1). The hydrolysis of chlorophene was studied by Greenwood (2003) in sterile aqueous buffered solutions at pH 4, 7 and 9. The concentrations of chlorophene were measured via HPLC-UV. In the preliminary test at 50 °C, the percentage of chlorophene which was hydrolysed during 5 days was less than 10%:6.5% loss was found at pH 7 and 2.1% at pH 9. No loss was found at pH 4. According to the guideline, the test substance is considered to be hydrolytically stable. Therefore, no further testing is required. The estimated half-lives of BCP at pH 7 and 9 were 44.4 and 37.4 days. Considering the hydrolytic stability determined under stringent temperature conditions and at different pH values (pH 4, 7 and 9) it is not expected that hydrolytic processes will contribute to the degradation of chlorophene in the aquatic systems. Hydrolysis is expected not to be a major degradation pathway for chlorophene.

Table: Results of hydrolysis of chlorophene

Guideline /
Test method



Initial TS concentration, C0 [mg/L]

Reaction rate constant, Kh [d]

Half-life, DT50

Coefficient of correlation, r2


EU method Annex V, C7 (92/69/EEC)

4, 7, 9


62.5 mg a.s./L

pH 4:
no dissipation

pH 7:
0.0156 day-1

pH 9:
0.0186 day-1

pH 4:
no dissipation

pH 7:
44.4 days

pH 9:
37.4 days


Greenwood (2003)