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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1978
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
1978
Reference Type:
review article or handbook
Title:
PubChem CID 8881 1,3-Dichloropropane
Author:
Kim S, Thiessen PA, Bolton EE, Chen J, Fu G, Gindulyte A, Han L, He J, He S, Shoemaker BA, Wang J, Yu B, Zhang J, Bryant SH. PubChem Substance and Compound databases. Nucleic Acids Res. 2016 Jan 4; 44(D1):D1202-13. Epub 2015 Sep 22 [PubMed PMID: 26400175] doi: 10.1093/nar/gkv951.
Year:
2018
Bibliographic source:
https://pubchem.ncbi.nlm.nih.gov/compound/1_3-dichloropropan
Reference Type:
review article or handbook
Title:
GESTIS Substance Database 1,3-Dichloropropane
Author:
IFA Institue for Occupational Safety and Health of the German Social Accident Insurance
Year:
2018
Bibliographic source:
http://gestis-en.itrust.de/pdf/create/Data_sheet.php

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: Methods for acute toxicity tests with fish, macroinvertebrates, and amphibians. U.S. EPA 1975
Version / remarks:
U.S.Environmental Protection Agency 1978. In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants. U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.40
Deviations:
not specified
Principles of method if other than guideline:
reliable data from handbook or collection of data but without specification of method
Stdy assumed to be reliable as based on U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1,3-dichloropropane
EC Number:
205-531-3
EC Name:
1,3-dichloropropane
Cas Number:
142-28-9
Molecular formula:
C3H6Cl2
IUPAC Name:
1,3-dichloropropane
Test material form:
liquid
Specific details on test material used for the study:
No data available

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Algae (not specified)

Study design

Test type:
not specified
Water media type:
freshwater
Total exposure duration:
96 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
ca. 61.1 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
not specified
Key result
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
ca. 40 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
not specified
Details on results:
U.S.Environmental Protection Agency 1978. In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants. U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
EC50 Algae 96 hours: 40 mg/l
Executive summary:

According to Ecotoxicological Data, reported by GESTIS, compiled by the US Environmental Protection Agency, selected and distributed by Technical Database Services (TDS, New York, 2009), the EC50 Algae, 96 hours is 40 mg/l for 1,3 -Dichloropropane. The original data compilation is U.S.Environmental Protection Agency 1978. In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants. U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.40