Registration Dossier
Registration Dossier
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EC number: 205-531-3 | CAS number: 142-28-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1978
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 978
- Reference Type:
- review article or handbook
- Title:
- PubChem CID 8881 1,3-Dichloropropane
- Author:
- Kim S, Thiessen PA, Bolton EE, Chen J, Fu G, Gindulyte A, Han L, He J, He S, Shoemaker BA, Wang J, Yu B, Zhang J, Bryant SH. PubChem Substance and Compound databases. Nucleic Acids Res. 2016 Jan 4; 44(D1):D1202-13. Epub 2015 Sep 22 [PubMed PMID: 26400175] doi: 10.1093/nar/gkv951.
- Year:
- 2 018
- Bibliographic source:
- https://pubchem.ncbi.nlm.nih.gov/compound/1_3-dichloropropan
- Reference Type:
- review article or handbook
- Title:
- GESTIS Substance Database 1,3-Dichloropropane
- Author:
- IFA Institue for Occupational Safety and Health of the German Social Accident Insurance
- Year:
- 2 018
- Bibliographic source:
- http://gestis-en.itrust.de/pdf/create/Data_sheet.php
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: Methods for acute toxicity tests with fish, macroinvertebrates, and amphibians. U.S. EPA 1975
- Version / remarks:
- U.S.Environmental Protection Agency 1978. In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants. U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.40
- Deviations:
- not specified
- Principles of method if other than guideline:
- reliable data from handbook or collection of data but without specification of method
Stdy assumed to be reliable as based on U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p. - GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,3-dichloropropane
- EC Number:
- 205-531-3
- EC Name:
- 1,3-dichloropropane
- Cas Number:
- 142-28-9
- Molecular formula:
- C3H6Cl2
- IUPAC Name:
- 1,3-dichloropropane
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- No data available
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- other: Algae (not specified)
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 61.1 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 40 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Details on results:
- U.S.Environmental Protection Agency 1978. In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants. U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- EC50 Algae 96 hours: 40 mg/l
- Executive summary:
According to Ecotoxicological Data, reported by GESTIS, compiled by the US Environmental Protection Agency, selected and distributed by Technical Database Services (TDS, New York, 2009), the EC50 Algae, 96 hours is 40 mg/l for 1,3 -Dichloropropane. The original data compilation is U.S.Environmental Protection Agency 1978. In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants. U.S.EPA Contract No.68-01-4646, Duluth, MN :9 p.40
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