Registration Dossier
Registration Dossier
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EC number: 223-888-3 | CAS number: 4109-96-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
Reference
Description of key information
There are no test data for the substance. However read across data for related substances gives the following results: a 48-hour EC50 of >100 mg/L and NOEC of ≥100 mg/L have been determined for the effects of related substance, Trimethoxysilane (CAS 2487-90-3), on mobility of Daphnia magna. It is likely that the test organisms were exposed to the hydrolysis products of the substance. A 48-hour EC50 value of >844 mg/L and NOEC of ≥844 mg/L have been determined for the effects of tetraethyl orthosilicate (CAS 78-10-4) on mobility of Daphnia magna. Under the static exposure conditions used in the test it is likely that the test organism will have been primarily exposed to the hydrolysis products of the test substance.
Key value for chemical safety assessment
Additional information
No test data for short-term toxicity to aquatic invertebrates are available for dichlorosilane.
An aquatic short-term toxicity study with invertebrates study with dichlorosilane is considered technically unfeasible because the substance is a gas at normal temperature and pressure and is expected to react violently and rapidly with water. This violent and rapid reaction of the gas with water would render aquatic ecotoxicology testing impossible and thus testing is waived on the basis of the technical difficulty to conduct such tests.
However, studies of short-term toxicity to invertebrates are available for the related substances trimethoxysilane (CAS 2487-90-3) and tetraethyl orthosilicate (CAS 78-10-4), as supporting evidence that the silanol hydrolysis product is not toxic and adding to the weight of evidence for not carrying out any further testing.
The relevant values are:
Trimethoxysilane (CAS 2487-90-3)
A 48-h EC50 value of >100 mg/l has been determined for the effects of trimethoxysilane on mobility of Daphnia magna based on nominal concentrations.
Tetraethyl orthosilicate (CAS 78-10-4)
A 48-h EC50 value of >844 mg/l has been determined for the effects of tetraethyl orthosilicate on mobility of Daphnia magna based on nominal concentrations.
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