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EC number: 213-214-6 | CAS number: 930-33-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 10253 (Water quality - Marine Algal Growth Inhibition Test with Skeletonema costatum and Phaeodactylum tricornutum)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Test substance: Triazolone
CAS#: 930-33-6
Stability: stable
Solubility: soluble in seawater
Appearance: white solid, powder with no odour
Date received: 01.09.2006
Storage: 20°C - Analytical monitoring:
- not specified
- Details on sampling:
- none
- Vehicle:
- no
- Details on test solutions:
- Dissolve the test substance in the culture medium. The concentration of this stock solution should correspond with the highest test dosage.
Mix the stock solution in a 1L glassflask on a magnetic stirrer for at least 30 min.
Based on the results from the preliminary test, the following test dosages were used for the definitive test: 2.0, 10, 50, and 250 mg/L - Test organisms (species):
- Skeletonema costatum
- Details on test organisms:
- Strain NIVA BAC 1 was used.
- Test type:
- static
- Water media type:
- saltwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
- Hardness:
- not specified
- Test temperature:
- 20 +/- 2.4 °C
- pH:
- 7.5 - 8.3
- Salinity:
- NA
- Conductivity:
- not specified
- Nominal and measured concentrations:
- nominal concentrations: 2.0, 10, 50, and 250 mg/L
- Details on test conditions:
- Two tests were performed. A preliminary test with 2 parallel test concentrations, followed by a definitive test wtih 3 parallel concentrations and 6 controls.
Inhibition is measured as a reduction in growth rate relative to control cultures grown under identical conditions.
light intensitiy has been in the range 6000-10000 lux. - Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 18 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- none
- Results with reference substance (positive control):
- growth rate inhibition of 1.5 mg/L 3,5-dichlorophenol = 24%
- Reported statistics and error estimates:
- none
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 72hEC50 for triazolone was found to be 18 mg/L.
The NOEC value was estimated to 2.0 mg/L. - Executive summary:
S. costatum testing has been performed on the test substance TO Triazolone base on ISO 10253.
The EC50 -value found for the test substance TO Triazolone (nominal whole product) after 72h was 18 mg/L. The EC10 was estimated to 4.2 mg/L, and the NOEC value was estimated to 2.0 mg/L.
Reference
none
Description of key information
Data based on experimental study results.
S. costatum testing has been performed on the test substance TO Triazolone base on ISO 10253.
The EC50 -value found for the test substance TO Triazolone (nominal whole product) after 72h was 18 mg/L. The EC10 was estimated to 4.2 mg/L, and the NOEC value was estimated to 2.0 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 18 mg/L
Additional information
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