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Administrative data

Endpoint:
auto-ignition temperature (liquids)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 July 2017 - 27 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.15 (Auto-Ignition Temperature (Liquids and Gases))
Deviations:
no
Qualifier:
according to guideline
Guideline:
DIN 51794 (Testing of mineral oil hydrocarbons - Determination of ignition temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
IEC 60079-4 (Electrical apparatus for explosive gas atmospheres. Part 4: Method of test for ignition temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Diethyl ethoxymethylenemalonate
EC Number:
201-725-7
EC Name:
Diethyl ethoxymethylenemalonate
Cas Number:
87-13-8
Molecular formula:
C10H16O5
IUPAC Name:
diethyl ethoxymethylenemalonate
Test material form:
liquid
Specific details on test material used for the study:
- Batch n°: JC170405
- Analytical purity: 99.5%
- Expiration date: 12 April 2018
- Storage condition: at room temperature

Results and discussion

Auto-ignition temperature (liquids / gases)
Key result
Auto-ignition temperature:
225 °C
Atm. press.:
>= 1 008 - <= 1 011 hPa

Any other information on results incl. tables

Preliminary test

The estimated auto-ignition temperature was 255°C.

Main study

The results of the main study on the determination of the auto-ignition temperature of the test item are given in the table below.

 Test  Volume [µL]  Auto-ignition temperature [°C]   Ignition delay [s]  Colour of the flame  Minimum auto-ignition temperature [°C]
 Test 1  70  253  43  orange/blue  229
   150  245  48    
   250  240  87    
   400  237  118    
   800  234  115    
   1000  229  209    
 Test 2  200  237  73   orange/blue  233
   600  234  252    
   900  233  174    
 Test 3  300  239  85   orange/blue  231
   700  234  183    
   950  231  281    

Ignition of the test item within 5 minutes after introduction was observed with each sample volume and with each test a minimum auto-ignition temperature was obtained. The maximum deviation between the three values was < 10°C. According to the guidelines, no further testing was required.

The lowest temperature at which ignition of the test item occurred was 229°C. This temperature was rounded down to the nearest multiple of 5°C giving an auto-ignition temperature of the test item of 225°C.

Applicant's summary and conclusion

Conclusions:
A commercially available auto-ignition temperature apparatus was used for the determination of the degree of auto-ignitability of JNJ-39005525-AAA (EMME).
The test item is auto-ignitable with an auto-ignition temperature of 225°C at 1008 - 1011 hPa.

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