Registration Dossier
Registration Dossier
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EC number: 203-271-5 | CAS number: 105-11-3
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- 1,4-benzoquinone dioxime
- Type of composition:
- boundary composition of the substance
- State / form:
- solid: particulate/powder
- >= 90 - <= 99.9 % (w/w)
- Reference substance:
- 1,4-benzoquinone dioxime
- Reference substance:
- 1,4-benzoquinone dioxime
- Reference substance:
- 1,4-benzoquinone dioxime
- This impurity is considered relevant for the classification and labelling of the substance
- Name:
- 1,4-benzoquinone dioxime
- Type of composition:
- legal entity composition of the substance
- State / form:
- solid: particulate/powder
- Related composition:
- 1,4-benzoquinone dioxime
- >= 90 - <= 99.9 % (w/w)
- Reference substance:
- 1,4-benzoquinone dioxime
- Reference substance:
- 1,4-benzoquinone dioxime
- Reference substance:
- 1,4-benzoquinone dioxime
- This impurity is considered relevant for the classification and labelling of the substance
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance has not demonstrated that it meets the ‘ready biodegradability’ screening criteria. The substance should be treated as potentially meeting the ‘P’ (not vP) criteria. The substance has demonstrated an n-octanol/water partition coefficient of log Kow << 4.0 via a reliable HPLC screening study (OECD TG 117) and with supporting QSAR predictions indicating comparable results. Therefore the conclusion for the substance is that it is not bioaccumulative in accordance with ECHA Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.11 as it does not fulfil the screening criteria for bioaccumulation potential. While a full dataset on chronic aquatic toxicity data is not available, the substance is not considered toxic based on consideration of the acute aquatic toxicity endpoints (including results of studies in algae, daphnia and fish per OECD TG 201, 202, and 203). Based on the available information, the substance is not classified as having CMR (category 1A or 1B) properties, nor does it show other evidence of toxicity criteria based on available sub-chronic and chronic studies for systemic toxicity or carcinogenicity (category 1A or 1B) studies in animals. In conclusion, the substance is not PBT and not vPvB.
- Likely routes of exposure:
Not applicable. Substance is not PBT/vPvB.
Referenceopen allclose all
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