Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04 June 2018 - 04 July 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

2016

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: isothermal thermogravimetry

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

< 0 Pa

Test no.:

#1

Temp.:

25 °C

Vapour pressure:

< 0 Pa

Key result

Test no.:

#2

Temp.:

20 °C

Vapour pressure:

< 0 Pa

Key result

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

< 0.001 Pa

Test no.:

#3

Temp.:

20 °C

Vapour pressure:

< 0 Pa

Test no.:

#3

Temp.:

25 °C

Vapour pressure:

< 0 Pa

Table: Results of the isothermal TGA analysis (test item)

Experiment	Temperature [°C]	Weight loss [µg/min]	νT [g/cm^2/h]	log νT	log PT	PT[Pa]
1	110	1.65181	1.97E^-4	-3.71	0.39	2.5
	120	3.28671	3.92E^-4	-3.41	0.78	6.0
	130	6.59689	7.87E^-4	-3.10	1.16	15
	140	12.4519	1.49E^-3	-2.83	1.52	33
2	110	2.83134	3.38E^-4	-3.47	0.69	4.9
	120	4.29937	5.13E^-4	-3.29	0.93	8.4
	130	7.92215	9.46E^-4	-3.02	1.27	18
	140	15.3535	1.83E^-3	-2.74	1.63	43
3	110	1.33953	1.60E^-4	-3.80	0.28	1.9
	120	2.30566	2.75E^-4	-3.56	0.58	3.8
	130	4.72438	5.64E^-4	-3.25	0.98	9.5
	140	8.80970	1.05E^-3	-2.98	1.32	21

 

Using the results of experiment 1 and experiment 2, the curve of log PT of the test item as function of the reciprocal temperature had a coefficient of correlation <0.99. Therefore, a third experiment was performed. The individual coefficients of correlation of the different experiments (log PT vs 1/T) were > 0.99.

Conclusions:

The vapour pressure of the substance at 20°C and 25°C was determined to be ≤ 4.5E-4 Pa and ≤ 8.7E-4 Pa, resp.

Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference compounds. Vapour pressure curves for the test item was constructed from individual measurements at 110°C, 120°C, 130°C and 140°C. The highest vapour pressure value from three consecutive individual experiments was concluded as the vapour pressure. Since the weight losses of the test item were obtained with a temperature program of above the melting temperature of the test item, the vapour pressure of the test item could be slightly overestimated. The vapour pressure of the substance at 20°C and 25°C was therefore reported as ≤ 4.5E-4 Pa and ≤ 8.7E-4 Pa, resp.

 

Description of key information

The isothermal TGA effusion method was applied for the determination of the vapour pressure in three experiments.

The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:

- at 20°C: between 4.2 x 10^-5 and 4.5 x 10^-4 Pa ==> 2.46e-4

- at 25°C: between 9.2 x 10 ^-5 and 8.7 x 10 ^-4 Pa

Key value for chemical safety assessment

Vapour pressure:

0.001 Pa

at the temperature of:

25 °C

Additional information

The weight losses of the test item were obtained with a temperature program of above the melting temperature of the test item.  According to this, the vapour pressure of the test item (which was, according to the method, extrapolated to 20°C and 25°C) could be slightly overestimated.