Registration Dossier

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 13, - April 02, 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
no
Type of method:
effusion method: Knudsen cell
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0.001 Pa
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0.001 Pa

Since the values were correlated by a linear relation (see attached file), the data could be fitted by linear regression.

 Parameters of linear regression

Parameter

Value

Slope

-5266.2

Intercept

14.8355

Correlation Coefficient r

-0.9986

Coefficient of Determination r2

0.9971

 

Results

The following vapour pressures were determined experimentally and considered as valid (mean and standard deviation given):

Experimentally Determined Vapour Pressures

T

T

P

Stand. Dev. P

RSD P

oC

K

Pa

Pa

%

30.0

303.2

2.67E-03

1.08E-04

4.0%

45.0

318.2

2.30E-02

1.18E-03

5.1%

60.0

333.2

1.01E-01

1.16E-02

11.4%

75.0

348.2

5.03E-01

3.01E-03

0.6%

In this table, E-03 represents * 10-3.

For the test substance Ethylphthalyl ethyl glycolate, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:

Vapour pressure at 20 °C:        7.43* 10-04Pa

Vapour pressure at 25 °C:        1.49* 10-03Pa

 

The linear regression of log p vs. 1/T gave a correlation coefficient r of - 0.9986, showing good repeatability and precision. Therefore, the determination is considered as valid.

The vapour pressure of the positive control met the validity criteria. Therefore, the study can be considered as valid.

Conclusions:
Vapour pressure of ethylphthalyl ethyl glycolate was measured using the Effusion method following Knudsen cell as described in OECD 104 .
From the measured values, the vapour pressure of the test substance ethylphthalyl ethyl glycolate was calculated as 0.000743 Pa at 20.0 °C, and 0.00149 Pa at 25 °C.

Description of key information

Vapour pressure of ethylphthalyl ethyl glycolate was measured using the Effusion method following Knudsen cell as described in OECD 104 .

From the measured values, the vapour pressure of the test substance ethylphthalyl ethyl glycolate was calculated as 0.000743 Pa at 20.0 °C, and 0.00149 Pa at 25 °C.

Key value for chemical safety assessment

Vapour pressure:
0.001 Pa
at the temperature of:
20 °C

Additional information