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Partition coefficient

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Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, A.8 (Schüttelmethode)
GLP compliance:
yes
Type of method:
other: Shake-flask method
Partition coefficient type:
octanol-water
Analytical method:
liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
< -1.5
Temp.:
25 °C
Remarks on result:
other: Imported from NONS file. pH not specified.
Conclusions:
The calculated log Pow of test substance at 25.0 °C is < -1.5.
Executive summary:

The study of determination of partition coefficient of test substance was carried out in accordance to 92/69/EWG, A.8 (Schüttelmethode) under GLP conditions.

The calculated log Pow of test substance at 25.0 °C is < -1.5.

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, A.8 (Schüttelmethode)
GLP compliance:
yes
Type of method:
other: Shake-flask method
Partition coefficient type:
octanol-water
Analytical method:
liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
-0.63
Temp.:
20 °C
Remarks on result:
other: Imported from NONS file
Conclusions:
The calculated log Pow of test substance at 20.0 °C is -0.63.
Executive summary:

The study of determination of partition coefficient of test substance was carried out in accordance to 92/69/EWG, A.8 (Schüttelmethode) under GLP conditions.

The calculated log Pow of test substance at 20.0 °C is -0.63.

Description of key information

Key study (001): Test method according to 92/69/EWG, A.8 (Schüttelmethode). GLP study. The partition coefficient (log Pow) of test substance at 20°C is -0.63.

Key study (002): Test method according to 92/69/EWG, A.8 (Schüttelmethode). GLP study. The partition coefficient (log Pow) of test substance at 25°C is < -1.5.

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.63
at the temperature of:
20 °C

Additional information