Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 616-995-5 | CAS number: 8018-01-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2014-01-22 to 2014-01-31
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- 0.2 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1.67 g/L
- Incubation duration:
- >= 0.5 - <= 2 h
- Temp.:
- 20 °C
- pH:
- >= 4 - <= 5
- Key result
- Water solubility:
- 0.2 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1.67 g/L
- Incubation duration:
- >= 0.5 - <= 2 h
- Temp.:
- 20 °C
- pH:
- >= 6 - <= 8
- Water solubility:
- 0.3 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1.67 g/L
- Incubation duration:
- >= 0.5 - <= 2 h
- Temp.:
- 20 °C
- pH:
- >= 9 - <= 10
- Conclusions:
- The water solubility of the substance was determined to be 0.2 mg/L at 20 °C and a pH between 6-8.
- Executive summary:
The determination of the solubility in water has been performed in duplicate according to EC method A.6 referring to OECD guideline 105. The solubility has been determined at 20 °C in the neutral (pH 6-8), acidic (pH 4-5) and alkaline (pH 9-10) range. The concentrations of the Test Item in the water solubility tests are determined by UV-spectroscopy according to CIPAC MT 165. The water solubility of the substance was determined to be 0.2 mg/L at 20 °C and a pH between 6-8.
Reference
Stirring time / h |
Absorbance at 281 nm |
Concentration / mg/L |
0.5 |
0.0260 |
0.214 |
0.5 |
0.0269 |
0.226 |
1 |
0.0260 |
0.214 |
1 |
0.0269 |
0.226 |
2 |
0.0266 |
0.222 |
2 |
0.0274 |
0.232 |
Mean (pH 4-5) |
- |
0.2 |
Stirring time / h |
Absorbance at 281 nm |
Concentration / mg/L |
0.5 |
0.0194 |
0.198 |
0.5 |
0.0197 |
0.202 |
1 |
0.0202 |
0.208 |
1 |
0.0201 |
0.207 |
2 |
0.0229 |
0.242 |
2 |
0.0235 |
0.249 |
Mean (pH 6-8) |
- |
0.2 |
Stirring time / h |
Absorbance at 281 nm |
Concentration / mg/L |
0.5 |
0.0209 |
0.266 |
0.5 |
0.0226 |
0.288 |
1 |
0.0229 |
0.292 |
1 |
0.0237 |
0.302 |
2 |
0.0247 |
0.315 |
2 |
0.0251 |
0.320 |
Mean (pH 4-5) |
- |
0.3 |
Description of key information
The water solubility of the substance was determined to be 0.2 mg/L at 20 °C and a pH between 6-8.
Key value for chemical safety assessment
- Water solubility:
- 0.2 mg/L
- at the temperature of:
- 20 °C
Additional information
The determination of the solubility in water has been performed in duplicate according to EC method A.6 referring to OECD guideline 105. The solubility has been determined at 20 °C in the neutral (pH 6-8), acidic (pH 4-5) and alkaline (pH 9-10) range. The concentrations of the test Item in the water solubility tests are determined by UV-spectroscopy according to CIPAC MT 165. The water solubility of the substance was determined to be 0.2 mg/L at 20 °C and a pH between 6-8.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
