Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
No information
Bibliographic source:
United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. (RTECS Database)
Reference Type:
review article or handbook
Title:
No information
Year:
1981
Bibliographic source:
U.S. Environmental Protection Agency: High Production Volume (HPV) Challenge: Monocyclic Aromatic Amines (MAA) Category.pdf - FDRL Report of Study 6771-E, December 17, 1981
Reference Type:
review article or handbook
Title:
No information
Year:
1988
Bibliographic source:
Lenga, R.E., The Sigma-Aldrich Library of Chemical Safety Data, ed.II, vol.1, 1988

Materials and methods

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
>= 1 130 - <= 1 480 mg/m³ air
Based on:
not specified
Exp. duration:
4 h
Clinical signs:
other: Somnolence (general depressed activity), dyspnoea

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information Criteria used for interpretation of results: EU