Registration Dossier
Registration Dossier
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EC number: 278-145-6 | CAS number: 75234-41-2
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The nominal concentrations tested were 1.0, 3.2, 10.0, 32.0 and 100 mg test article/L and a control without any additions.
The test results:
Highest concentration tested without toxic effects (NOEC): 10 mg test article/L
Lowest concentrations tested with toxic effects (LOEC): 32.0 mg test article/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 10 mg/L
Additional information
The influence of the test item on reproduction and survival rate of daphnia magna was investigated in a 21 days semistatic test according to the OECD Guideline for testing of Chemicals, Section 2, No. 202, adopted 4 April 84.
The test was performed in a compliance with the Good Laboratory practice Regulations.
The nominal concentrations tested were 1.0, 3.2, 10.0, 32.0 and 100 mg test article/L and a control without any additions.
The test results:
Highest concentration tested without toxic effects (NOEC): 10 mg test article/L
Lowest concentrations tested with toxic effects (LOEC): 32.0 mg test article/L
In the concentration of 10 mg test article/L the analysed concentrations in the freshly prepared test media amounted in the mean to 82.4 % of the nominal value. In the freshly prepared test media of the concentration of 100 mg/L on day 0 only 54.4 % of the nominal value was measured, but in the lower concentration of 10 mg/L, prepared in sequential dilutions out of the higher concentrations, the measured concentration amounted to 84.7 % at that date. On the next analytical date 90.5 % of the nominal value of the concentration of 100 mg test article/L was determined. Since in the samples of the stock solutions always concentrations between 81.3 and 88.7 % of the nominal values were measured and the test article was sufficiently stable under test conditions, all reported results are related to the nominal concentrations of the test article.
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