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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP-study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Deviations:
not specified
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Details on test material:
- Physical state: yellow crystalline solid block
- Storage condition of test material: room temperature, in the dark
- Other: Sponsor's identification: OS 144267

Results and discussion

Test substance stable:
not determined
Details on results:
The standard OECD method 116 was not applicable to this test material because it has been observed as miscible all proportions with standard fat at 37.0 ± 0.5 °C.

Any other information on results incl. tables

Results - Observations and concentrations relating to the samples

Sample   Concentration (% w/w)  Observation
 1  6.08  Single phase light yellow liquid
 2  48.1  Single phase light yellow liquid
 3  94.3  Single phase light yellow immobile liquid

Applicant's summary and conclusion

Conclusions:
The test substance was observed as miscible in all proportions with standard fat at 37.0 ± 0.5 °C.