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EC number: 406-040-9 | CAS number: 125643-61-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Phototransformation (air, water, soil)
Phototransformation in air, water and in soil are no mandatory endpoints for the registration of a chemical under REACH Regulation (EC) 1907/2006 for substances produced between 10 - 100 tons/year.
Hydrolysis
Unfortunately, no results can be reported for this mandatory endpoint under REACH regarding Benzenepropanoic acid, 3,5 -bis(1,1 -dimethylethyl)-4 -hydroxy-,C7 -9 branched alkyl esters (CAS 125643 -61 -0). However, data from two read-across substances are available.
Butyl 3.5-bis(1.1-dimethylethyl)-4-hydroxybenzenepropanoate (CAS 52449-44-2) was tested for hydrolysis using Method C7 of Commission Directive 92/69/EEC (O´Connor, 2000). Three buffer solutions were prepared for pH4, 7 and 9, respectively. At pH 4 half life of greater than 1 year at 25 °C was determined. At pH 7 it was not possible to accurately quantify the rate kinetics due to the slow rate of hydrolysis even at elevated temperatures, therefore the hydrolytic half life has been estimated as greater than 1 year using the software HYDROWIN v1.67. At pH 9, a rate constant of 2.78 x 10^-7 s-1 (0.000000278 s-1) and an estimated half-life of 28.9 days at 25 °C was reported.
The hydrolysis potential of Benzenepropanoic acid, 3,5 -bis(1,1 -dimethylethyl)-4 -hydroxy-2 -ethylhexylester (CAS 144429 -84 -5) was determined according to OECD Guideline 111 (Woolley and Mullee, 2007). Again, three buffer solutions were prepared for pH4, 7 and 9. The concentration of the sample solution was determined by high performance liquid chromatography (HPLC). No rate constant could be determined at pH 4 and 7, whereby the half-live at 25 °C will be greater than 1 year. At pH 9 a rate constant of 0.000000528 s-1 (5.28 x 10^-7 s-1) is reported as well as a half-life of 15.2 days at 25 °C.
Henry´s Law constant / Distribution modelling
Henry Law Constant (calculated by EPI-Win): 0.266 Pa*m3/mol
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