Registration Dossier
Registration Dossier
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EC number: 272-574-2 | CAS number: 68890-66-4
Additional physico-chemical information
Administrative data
Link to relevant study record(s)
Description of key information
Octopirox (piroctone olamine) is an an antidadruff active mainly used for hair shampoos. The content in hair shampoos generally ranges between 0.1 and 1 % (m/m). After use Octopirox reaches with the waste water the canalisation and finally the sewage treatment plant. Along the way it has a lot of opportunities to come in conact with urbiquitary iron(III) ions and to form complexes with them. It is known that Octopirox forms stable complexes with metal ions (e.g. Fe2+, Fe3+, Al3+), which are nearly insoluble in water. The formation of stable complexes is crucial to reduce the concentration of dissolved Octopirox in the aquatic environment, because its biodegradability is low and its fish toxicity is considerably high. The elimination of dissolved Octopirox from aquatic environment by complex formation with iron(III) was studied.
Results:
The elimination rate caused by complexation with iron(III) ions is >99.7 %. The remaining Octopirox content is approx. 10-fold lower than the EC50 concentration for fish toxicity.
Additional information
Trial |
Initial Octopirox concentration [mg/L] |
Octopirox concentration after 24 h contact with iron(III) [mg/L] |
Octopirox concentration after 24 h contact with iron(III) [mg/L] |
| A | 18000 |
60 | (282) |
| B | 18000 | 54 | 39 |
| C | 18000 | 46 | 39 |
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