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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

No effects up to the limit of water solubility for Scenedesmus subspicatus (EU Method C.3)

Key value for chemical safety assessment

Additional information

There are no studies available on the algal toxicity of Fatty acids, C8-10, 2-ethylhexyl esters (CAS No. 649747-80-8). The assessment was, therefore, based on a study conducted with the structurally similar substance isopropyl myristate (CAS No. 110-27-0), as part of a read-across approach. This is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of similarity, nearest physico-chemical properties) read-across substance was entered into IUCLID. Nevertheless, as can be seen in the data matrix of the category justification in Section 13, all reliable data in the category support the hazard assessment for this endpoint, by showing a consistent pattern of results.

The key study with isopropyl myristate (CAS No. 110-27-0) was performed as a limit test according to the EU Method C.3 and GLP (Rieche, 1995). The test organism Scenedesmus subspicatus was exposed to the test substance in a static system for 72 hours, at the nominal test concentration of 100 mg/L. The test was performed with and without separation of undissolved test substance. With undissolved test substance present, algal growth was significantly inhibited. However, when the undissolved phase was separated, no effects on growth were observed. It can, therefore, be concluded that the substance has no toxic effects on the test organism up to the limit of water solubility.

Thus, based on theabove mentioned result, and due to the structural and profile similarities of the two substances, as are explained with in the overall endpoint summary 6.1 it can be concluded that no toxicological effects on algae are expected up tothe limit ofwater solubility for Fatty acids, C8-10, 2-ethylhexyl esters (CAS No. 649747-80-8).