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EC number: 205-617-0
CAS number: 144-15-0
The substance tris(2-ethylhexyl)
2-(acetyloxy)propane-1,2,3-tricarboxylate is an extremely water -
insoluble substance (0.00000078 mg/L at 20°C, est. by US EPA program
WSKOWWIN v.142) for which no acute toxicity to daphnids and algae - the
two most sensitive species - was recorded at levels up to the Water
Accommodated Fraction of nominal 100 mg test item/L, the concentration
representing the limit of solubility.
2-(acetyloxy)propane-1,2,3-tricarboxylate is not rapidly degradable and
has an experimentally determined log Pow ≥ 4, indicating a potential to
bioaccumulate. Normally, according to the Classification, Labelling and
Packaging Regulation EC (No) 1272/2008 the substance needs to be
classified as Aquatic Chronic 4 (H413) unless other scientific evidence
exists; such evidence includes chronic toxicity NOECs > 1 mg/L (or at
the solubility level).
A chronic toxicity test on the
structural analogue tributyl 2-acetoxypropane-1,2,3-tricarboxylate (CAS
77-90-7) is available for Daphnia Magna: the NOEC from this test amounts
to >= 1.11 mg/L, representing a conservative estimate of aquatic
As conclusion, taking all these facts
and the low bioavailability (low bioconcentration potential, very high
adsorption potential to soil and rapid degradation in air) of the
substance tris(2-ethylhexyl) 2-(acetyloxy)propane-1,2,3-tricarboxylate
into account, it does not need to be classified
and labelled according to Regulation (EC) No 1272/2008 of the European
Parliament and of the Council since no acute/chronic toxicity is
expected up to its limit of solubility in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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