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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: OECD guideline study, published in lierature, minor restrictions in reporting, but otherwise adequate for assessment

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Aquatic toxicological aspects of dithiocarbamates and related compunds. I. Short-term toxicity tests.
Author:
van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G, Vergouw WHA, Griffioen NPS and Luijken MW
Year:
1985
Bibliographic source:
Aquatic Toxicology, 7: 145-164
Reference Type:
other: thesis
Title:
Aquatic Toxicology, 7: 145-164
Author:
Aquatic Toxicology, 7: 145-164
Year:
1986
Bibliographic source:
Thesis University of Utrecht

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
no
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Diethylamine
EC Number:
203-716-3
EC Name:
Diethylamine
Cas Number:
109-89-7
Molecular formula:
C4H11N
IUPAC Name:
diethylamine
Details on test material:
- Name of test material (as cited in study report): Sodium diethyldithiocarbamate (NaDEDC)
- Supplier: Fluka AG (Buchs, Switzerland)
- Purity: 99%
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Water solubility: very well soluble

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Chlorella pyrenoidosa

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Test temperature:
20± 1 °C

Details on test conditions:
TEST SYSTEM
- Test vessel: Erlenmeyer flasks
- Type (delete if not applicable): closed
- Material, size, headspace, fill volume: 200 ml
- Aeration: placed on a mechanical shaker
- Initial cells density: approximately 10E8 cells .1E-1 (100 ml)
- The tests were carried out in triplicate.

TEST MEDIUM / WATER PARAMETERS
- The composition of the medium used is given elsewhere (Van Leeuwen and Maas, 1985).

OTHER TEST CONDITIONS
- Light intensity and quality: placed under fluorescent light (7.5 W/m²)
Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
56 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

Validity criteria fulfilled:
yes