Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary source. Only limited data.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Assessment of Data Availability and Test Plan for Primary Amines
Author:
American Chemistry Council Amines HPV Panel
Year:
2002
Bibliographic source:
High Production Volume (HPV) Chemicals Challenge
Reference Type:
secondary source
Title:
IUCLID data set
Author:
American Chemistry Council Amines HPV Panel
Year:
2002

Materials and methods

GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
609-333-1
EC Number:
609-333-1
Cas Number:
37143-54-7
Molecular formula:
C4 H11 N O
IUPAC Name:
609-333-1

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male/female

Administration / exposure

Duration of exposure:
24 hours

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
ca. 3 000 mg/kg bw

Applicant's summary and conclusion