Registration Dossier
Registration Dossier
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EC number: 610-150-4 | CAS number: 438193-30-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1171067-76-7
- Cas Number:
- 1171067-76-7
- IUPAC Name:
- 1171067-76-7
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
- Details on study design:
- The carefully stoppered bottles were incubated at 20.0°C in the dark. The zero-time bottles were analysed immediately for dissolved oxygen by the
electrode method. At least duplicate bottles of all series were analysed at time intervals over the 28 days incubation.
Sampling frequency: 0, 1, 2, 5, 8, 12, 16, 19, 23 and 28 days
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 1
- Sampling time:
- 1 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 4
- Sampling time:
- 2 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0
- Sampling time:
- 12 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- For the test item, no marked reduction of the O2 concentration was observed. Throughout the experiment small values of O2 uptake were
measured on the second day. As the results do not exceed 4 per cent and not any O2 uptake was measured during the further test they can not be
interpreted as a degradation of the test item.
BOD5 / COD results
- Results with reference substance:
- 58% after 2 days, 77% after 5 days and 81% after 12 days
Applicant's summary and conclusion
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The pass Ievel for ready biodegradation ( 60 per cent degradation) was not reached. Thus in the test for ready biodegradability the test item seems
to be not readily biodegradable.
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