Registration Dossier
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EC number: 447-830-3 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Sewell and Mckenzie (2004): The 48-hour EL50 for the test material to Daphnia magna based on nominal loading rates was 150 mg/L loading rate WAF with 95 % confidence limits of 130 - 180 mg/L loading rate WAF. The No Observed Effect Loading rate was 56 mg/l loading rate WAF.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 150 mg/L
Additional information
The short-term toxicity to aquatic organisms was examined using Daphnia magna. Following a preliminary range-finding test, twenty daphnids (2 replicates of 10 animals) were exposed to Water Accommodated Fractions (WAFs) of the test material over a range of nominal loading rates of 10, 18, 32, 56, 100, 180, 320, 560 and 1000 mg/L for 48 hours at a temperature of approximately 21 ºC under static test conditions. The number of immobilised Daphnia were recorded after 24 and 48 hours.
The study was conducted in accordance with the OECD 202 and EU Method C.2 guidelines. The study was conducted to GLP standard, in a certified laboratory. The study is assigned a reliability score of 1 in accordance with Klimisch et. al. (1997).
The 48-hour EL50 for the test material to Daphnia magna based on nominal loading rates was 150 mg/L loading rate WAF with 95 % confidence limits of 130 - 180 mg/L loading rate WAF. The No Observed Effect Loading rate was 56 mg/L loading rate WAF.
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