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EC number: 619-057-3 | CAS number: 94667-33-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- The read across to Bardap 26 is supported by a set of bridging studies for DDAC and ADBAC demonstrating the similarity in physico-chemical, toxicological, ecotoxicological and movement and fate properties of these quaternary substances. The quaternary ammonium compound (Bardap 26) for which read across is requested, and the two substances used for read across (DDAC and ADBAC) belong to the family of cationic surfactants. Within this family they form a well-defined subgroup of substances with similar chemical structure; (1) one or two hydrophobic, non-branched alkyl chains with a main chain length distribution of C10-16, (2) one to three methyl group substituents and (3) a hydrophilic group carrying a positively charged quaternary nitrogen atom.
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.018 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.032 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.01 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks:
- survival
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.018 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks:
- survival
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.018 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- other: Condition
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.032 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- other: Condition
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- >= 0.018 - <= 0.056 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- LC50
- Effect conc.:
- 0.023 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 0.0034 - 0.0057 mg/l
Reference
Description of key information
One key study is available to determine the long-term toxicity of Bardac 22 (read-across from structural analog, Didecyldimethylammonium Chloride) to Daphnia magna. The study was conducted in accordance with OECD Guideline 211 with no deviations and GLP compliant. The Daphnia were exposed to the test material at concentrations of 3.2, 5.6, 10, 18, 32 and 56 mg/L for 21 days. The NOEC and LOEC for reproductive effects were determined to be 0.018 mg/L and 0.032 mg/L, respectively. The NOEC and LOEC for survival effects were determined to be 0.010 mg/L and 0.018 mg/L, respectively and for condition, the NOEC and LOEC were determined
to be 0.018 mg/L and 0.032 mg/L, respectively.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.01 mg/L
Additional information
In a study conducted in accordance with OECD Guideline 211, Daphnia magna were exposed to the test material, Bardac 22 with radiolabelled Didecyldimethylammonium Chloride for 21 days, at concentrations of 0, 0.0032, 0.0056, 0.010, 0.018, 0.032, 0.056 mg/l (actual test concentrations, 0, 0.0035, 0.0062, 0.0097, 0.0189, 0.0329, 0.0592 mg/l). The study was conducted in an intermittent flow through system which provided ca. 250 ml of test substance in dilution water every 51 minutes. Four replicates of each concentration (3.2, 5.6, 10, 18, 32 and 56 mg/l) and control media were tested with 10 test animals (<24-hours old). Under the conditions of this study, the NOEC and LOEC for reproductive effects were determined to be 0.018 mg/l and 0.032 mg/l, respectively. The NOEC and LOEC for survival effects were determined to be 0.010 mg/l and 0.018 mg/l, respectively and for condition, the NOEC and LOEC were determined to be 0.018 mg/l and 0.032 mg/l, respectively.
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