Registration Dossier
Registration Dossier
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EC number: 291-905-1 | CAS number: 90506-43-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
Refer to attached document - Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Validity criteria fulfilled:
- yes
- Conclusions:
- Available data from 1-Octadecanol, phosphate, potassium salt were used to evaluate toxicity to microorganisms for Phosphoric acid, C12-18-alkyl esters, potassium salts.
The toxicity to microorganisms of the read-across substance 1-Octadecanol, phosphate, potassium salt was tested in a study according to OECD guideline 209 using activated sludge from a domestic sewage treatment plant as inocumlum.
No significant inhibition was observed at the highest test concentration of 1000 mg/L 1-Octadecanol, phosphate, potassium salt.
3h NOEC ≥ 1000 mg/L
3h EC20 > 1000 mg/L
3h EC50 > 1000 mg/L
Reference
Description of key information
A 3h-NOEC of > 1000 mg/L for toxicity to microorganisms was determined for Phosphoric acid, C12-18 alkyl esters, potassium salts based on read-across information.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
Available data from 1-Octadecanol, phosphate, potassium salt were used to evaluate toxicity to microorganisms for Phosphoric acid, C12-18-alkyl esters, potassium salts.
The toxicity to microorganisms of the read-across substance 1-Octadecanol, phosphate, potassium salt was tested in a study according to OECD guideline 209 using activated sludge from a domestic sewage treatment plant as inocumlum.
No significant inhibition was observed at the highest test concentration of 1000 mg/L 1-Octadecanol, phosphate, potassium salt.
3h NOEC ≥ 1000 mg/L
3h EC20 > 1000 mg/L
3h EC50 > 1000 mg/L
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