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EC number: 203-965-8 | CAS number: 112-38-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995-06-06 to 1995-10-16
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No test surrogate or analogue material - Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: saturated test solution (SL), 62.5% SL, 39.1% SL, 24.4% SL, 15.3% SL and 9.5% SL
- Sampling method: Aliquots were taken at 0 and 48 hours
- Sample storage conditions before analysis: not reported - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: Test solutions were prepared the same day the test was conducted. 100 mg of the test item per 1 litre of the test medium were stirred for 5 hours at 30°C followed by 24 hours at 20°C using a magnetic stirrer. Thereafter, the saturated solution was centrifuged for 15 minutes at 2800 g for and the solution was decanted.
- Controls: Test medium only
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): none
- Evidence of undissolved material (e.g. precipitate, surface film, etc): none reported - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain: STRAUS
- Source: in-house culture
- Age at study initiation (mean and range, SD): < 24 h
- selected by sieving (0.56 mm mesh)
- Method of breeding: not reported
- Feeding during test: no
ACCLIMATION
- Acclimation period: no
- Acclimation conditions (same as test or not): yes - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- No post exposure observation period
- Hardness:
- Test was performed in a ISO 6431 test medium.
- Test temperature:
- 20 - 22 °C
- pH:
- initial: 6.46
at 48 h: 6.84 - 7.68 - Dissolved oxygen:
- at 48 h: 8.4 - 8.7 mg/L
- Salinity:
- Test was performed in a ISO 6431 test medium.
- Nominal and measured concentrations:
- nominal: 100% saturation (S) = 100 mg/L, 62.5% S, 39.1% S, 24.4% S, 15.3% S, 9.5% S, and 6% S (the lowest test concentration was not analytically verified since it was expected to be below the LOQ.
measured at 0 h: 106.3, 65.2, 41.8, 25.5, 17.7,10.3 mg/L
measured at 48 h: 106, 63, 36.6, 22.8, 15.1, 7 mg/L - Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: glass beaker, 250 mL, not reported
- Aeration: ISO medium was aerated to saturation prior to test
- Type of flow-through (e.g. peristaltic or proportional diluter): not applicable
- Renewal rate of test solution (frequency/flow rate): --
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
- No. of vessels per control (replicates): 2
- No. of vessels per vehicle control (replicates): not applicable
- Biomass loading rate: not reported
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: ISO 6341
- Culture medium different from test medium: no
- Intervals of water quality measurement: 0 and 48 h
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: continuous dark
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : immobility at 24 and 48 h
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 0.63
- Justification for using less concentrations than requested by guideline: not applicable
- Range finding study
- Test concentrations: 100% to 0.1% of saturation
- Results used to determine the conditions for the definitive study: yes - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 33 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL: not calculable
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 28 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL: 16 - 38 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 10.3 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: At 48 h, 5% immobility was found at this treatment level.
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 65.2 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Results with reference substance (positive control):
- - Results with reference substance valid?
- EC50/24h : 0.94 mg/L
- Test was conducted 06.09.1995 - Reported statistics and error estimates:
- Probit analysis
- Validity criteria fulfilled:
- yes
- Remarks:
- Mortality in the control did not exceed 10%. Oxygen concentration did not fall below 2 mg/L in any treatment during the test period.
- Conclusions:
- A 48h-EC50 value of 28 mg/l was calculated using Probit analysis.
- Executive summary:
The acute effects of undecylenic acid to the waterflea Daphnia magna were investigated in a 48 -hour test according to OECD Guideline 202, Pt. 1. Young daphnids less then 24 -hours old were exposed under static conditions to a series of concentrations initially measured as < LOQ (7 mg/L), 10.3, 17.7, 25.5, 41.8, 65.2 and 106.3 mg/L, and, aditionally, a blank control was set up. For all treatment groups, the concentration remained during the test period at >80% of initial with the exception of the second lowest for which 68% (7 mg/L) were found at 48 hours. Since this test group was not important for the EC50 calculation, the initially measured concentrations were used for calculating the toxic endpoints. At the end of the test period, immobilisation was 10%, 5%, 5%, 10%, 25%, 95%, 100% and 100% in the control, <LOQ, 10.3, 17.7, 25.5, 41.8, 65.2 and 106.3 mg/L treatment group, respectively. On basis of these findings, the 48h-EC50 value was calculated as 28 mg/L using Probit analysis.
Reference
Table 1:Acute toxic effects of undecylenic acid to Daphnia magna under static exposure conditions
Test concentration |
Immobilisation |
||||
Nominal |
Measured |
|
|
||
Saturation of test medium (%) |
Test start – 0 h (mg/L) |
Test end – 48 h (mg/L) |
0 h / 48 h (%) |
24 h (number / %) |
48 h (number / %) |
Control |
n.d. |
n.d. |
n.a. |
1 / 5 |
2 / 10 |
6.0 |
< LOQ |
< LOQ |
n.a. |
1 / 5 |
1 / 5 |
9.5 |
10.3 |
7 |
68.0 |
1 / 5 |
1 / 5 |
15.3 |
17.7 |
15.1 |
85.3 |
2 / 10 |
2 / 10 |
24.4 |
25.5 |
22.8 |
89.4 |
3 / 15 |
5 / 25 |
39.1 |
41.8 |
36.6 |
87.6 |
10 / 50 |
19 / 95 |
62.5 |
65.2 |
63.0 |
96.6 |
20 / 100 |
20 / 100 |
100 |
106.3 |
106.0 |
99.7 |
20 / 100 |
20 / 100 |
n.d. = not determined;
n.a. = not applicable;
LOQ = limit of quantification (7 mg/L)
Description of key information
The acute effects of undecylenic acid to the water flea Daphnia magna were investigated in a 48-hour test according to OECD Guideline 202, under static conditions. The 48h-EC50 value was equal to 28 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 28 mg/L
Additional information
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