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EC number: 272-347-8 | CAS number: 68814-95-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Bioaccumulation:
QSAR estimations are available revealing a Log Kow of 11.83. The value indicates potential for bioaccumulation. In the following the assessment of the bioaccumulation potential Amines, tri-C8-10-alkyl will be based on a worst-case log Kow of 11.83. Estimations of the BCF were performed with three different models. The results are evaluated in a weight-of-evidence approach.
A BCF calculation using the CATALOGIC v.5.11.9 BCF base-line model vs.2.05 is available for Amines, tri-C8-10-alkyl (CAS: 68814-95-9). The BCF model calculates the BCF implicating the estimated log Kow value of 11.83. Furthermore, the influence of mitigating factors like ionization of the molecule, water solubility, size and metabolism are also considered by the model. Taking into account these mitigating factors the BCF is reduced to 7.43 (log BCF = 0.871).
For molecular size a cut-off value is discussed in the literature indicating a limited bioaccumulation potential. The PBT working group on hazardous substances discussed a maximum diameter of > 17.4 Å (Comber et al., 2006).The DiamMax-Average of the test item is determined to be 20.35 Å depending on its conformation.
EPISuite v4.1/BCFBAFv3.01: The BCF was estimated to be 14.6 L/kg based on the regression-based method and the BCF estimation based on Arnot-Gobas upper trophic predict a BCF of 193 L/kg. Metabolism in fish was predicted to produce 4 types of primary metabolites. A biotransformation half-life of 52 days was estimated for a fish of 10 g wet weight.
Furthermore, the Guidance on information requirements and chemical safety assessment Chap. R11 PBT Assessment indicates that substances with a modeled Log Kow of > 10 are assumed to have a limited bioaccumulation potential.
CONCLUSIONS
Based on the results from Catalogic , BCFBAF and the information given the Guidance on information requirements and chemical safety assessment Chap. R11 PBT Assessment , it is concluded that the substance is not significantly bioaccumulative.
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