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Diss Factsheets
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EC number: 287-836-1 | CAS number: 85586-34-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 72 hour growth inhibition toxicity study was performed according to the 87/302/EEC page 89-94 Algal Inhibition Test guideline. Scenedesmus subspicatus was exposed for 72hours to nominal concentrations of TK 11278. Based on the initial measured exposure concentrations the 72 hour EbC50 was calculated to be 8 mg/L (with 95% confidence limits of 5.4 to 11.6 mg/L), the corresponding no-observed effect concentration (NOEC) was 0.7 mg/L.
Key value for chemical safety assessment
Additional information
A 72 hour growth inhibition toxicity study was performed according to the 87/302/EEC page 89-94 Algal Inhibition Test guideline. Scenedesmus subspicatus was exposed for 72 hours to nominal concentrations of TK 11278. Based on the initial measured exposure concentrations the 72 hour EbC50was calculated to be 8 mg/L (with 95% confidence limits of 5.4 to 11.6 mg/L), the corresponding no-observed effect concentration (NOEC) was 0.7 mg/L (Grade, 1993).
The water solubility of ESBO is estimated to be <0.02 µg/L, categorised as insoluble REACH. Ideally aquatic toxicity studies should not be conducted above the limit of water solubility, the study reported here tested nominal concentrations up to 100 mg/L. According to Annex VII a growth inhibition study with algae is required unless there are mitigating factors such as the test substance is insoluble, this is the case for ESBO. Therefore, the algae study is reported here for information only (this study was also reported in the OECD SIDS Initial Assessment Report for SIAM 22, 18 -21 April 2006), the endpoint will not be used for PNEC setting or in any risk assessment.
ESBO forms the core of the structure of soybean oil, epoxidised, ether with ethylene glycol, which has similar low solubility in water. The ether linkages and attachment of ethylene glycol (which itself has low intrinsic toxicity to aquatic organisms, as shown in the summarised RIVM review paper) is not expected to modify the acute toxicity of soybean oil, epoxidised, ether with ethylene glycol significantly, compared to that of ESBO.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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