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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1994
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Analytical method:
photometric method
Type:
Pow
Partition coefficient:
41.5
Temp.:
25 °C
pH:
5.75
Type:
log Pow
Partition coefficient:
1.62
Temp.:
25 °C
pH:
5.75

mean value of 3 measurements

Conclusions:
The partition coefficient n-octanol/water of the test substance was determined to be logPow= 1.62 at 25°C at pH 5.75.
Executive summary:

In this guideline (OECD X) study conducted to GLP standards, the partition coefficient n-octanol/water of the test substance

(EC 231-272-0) was determined to be was determined to be logPow= 1.62 at 25°C at pH 5.75

Description of key information

 Study conducted to generally recognised scientific standards with GLP

Key value for chemical safety assessment

Log Kow (Log Pow):
1.62
at the temperature of:
25 °C

Additional information

The measurement was carried out by shake-flask method and was determined to be logPow= 1.62 at 25°C at pH 5.75