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Short-term toxicity to aquatic invertebrates

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Description of key information

2,2-dimehtyloxiran is acutely harmful to aquatic invertberates

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
64.8 mg/L

Additional information

To determine the toxicity of 2,2 -dimethyloxiran to aquatic invertebrates, a GLP study according to EU method C.2 using Daphnia magna was performed. The calculated EC50 (48h) value in this study was 64.8 mg/L, related to the analytically verified nominal concentrations (BASF SE 1999). The toxicity of the analogous substance 1,2 -epoxybutane on Daphnia magna was tested in an acute toxicity test (BASF 1988). The EC50 (48h) determined to be 70 mg/L.

As the results lie in the same range, a read-across on other aquatic endpoints (acute toxicity to fish an algae) is regarded as valid.