Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 207-325-9 | CAS number: 462-34-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to algae.
Key value for chemical safety assessment
Additional information
In water, the tetrahydrofuran - boron trifluoride complex rapidly decomposes to form tetrahydrofuran and boron trifluoride dihydrate. The latter reacts further to boric acid and fluoroboric acid, which finally hydrolyses to yield hydrofluoric acid/ fluoride ions (BUA, 2005). The assessment of fish toxicity was therefore based on studies on the products of hydrolysis.
Bringmann and Kuhn reported a toxic threshold concentration of 3700 mg/L for eight days exposure of Scenedesmus quadricauda to tetrahydrofuran (Bringmann and Kuhn, 1976).
The toxicity of boron trifluoride dihydrate was investigated following the guideline of Directive 92/69/EEC, method C3 and according to GLP. The EC50 value based on growth rate was determined to be greater than 500 mg/L (Arkema, 2005).
The toxicity of boron toSpirodella polyrrhizawas determined by Davis et al. 2002 using standard methods. Frond production is apparently a more sensitive endpoint than either growth rate or the presence of abnormal fronds. Frond production inS. polyrrhizawas significantly reduced at 3.55 mg B/L. Significant reductions in growth rate and the percentage of abnormal (chlorotic, necrotic, and dead) fronds were observed at 18.9 and 22.4 mg B/L, respectively. The EC50for frond production, frond growth rate, and abnormal fronds were 14.3, 11.7, and 17.7 mg B/L, respectively. Davis et al. (2002) reported a NOEC value of 6.1 mg- B/L for the duckweedSpirodella polyrhiza. They reported endogenous boron level of 0.9 mg- B/L from the various nutrient media used.
Another non published data, an OECD 201 study ofSelenastrum capricornutum(Hanstveit and Oldersma 2000) reported a NOEC concentration of 17.5 mg-B/L..
Other studies reported NOEC values were obatined forChlorella pyrenoidosa(10 mg-B/L),Scenedesmus subspicatus(24 mg-B/L),Anacystis nidulans(50 mg-B/L) andLemna minor(60 mg-B/L) are also available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

EU Privacy Disclaimer
This website uses cookies to ensure you get the best experience on our websites.