Registration Dossier
Registration Dossier
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EC number: 229-654-7 | CAS number: 6640-24-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- In silico prediction.
Tox Boxes 2.9 is the in house software for the prediction of basic toxicity endpoints in chemicals. Predictions are made analyzing the chemical structure and based upon large validated databases and QSAR models, in combination with expert knowledge of organic chemistry and toxicology. - GLP compliance:
- not specified
- Test type:
- other: in silico prediction
Test material
- Reference substance name:
- 1-(m-chlorophenyl)piperazine
- EC Number:
- 229-654-7
- EC Name:
- 1-(m-chlorophenyl)piperazine
- Cas Number:
- 6640-24-0
- Molecular formula:
- C10H13ClN2
- IUPAC Name:
- 1-(3-chlorophenyl)piperazine
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 350 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- other: alert
- Remarks:
- Criteria used for interpretation of results: expert judgment
- Conclusions:
- Tox Boxes 2.9 prediction
DL50 oral rat =350 mg/kg
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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